2-(Formylamino)phenylboronic acid pinacol ester

CAS 480425-36-3C13H18BNO3Chemical Synthesis

2-(Formylamino)phenylboronic acid pinacol ester (CAS: 480425-36-3, Formula: C13H18BNO3) is a stable organoboron compound with a molecular weight of 247.10 g/mol. It serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure features a boronic ester functional group attached to a phenyl ring substituted with a formamide moiety, making it useful for introducing specific structural elements in the synthesis of complex molecules, including pharmaceuticals and advanced materials.

IUPAC: 2-Formamidophenylboronic acid pinacol ester,N-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide
Synonyms: 2-Formamidophenylboronic acid pinacol esterN-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide

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2-(Formylamino)phenylboronic acid pinacol ester (C13H18BNO3) — chemical structure, CAS 480425-36-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Aryl Boronate EstersBoronate EstersChemical SynthesisOrganometallic Reagents

01 /Applications

Suzuki-Miyaura Coupling Reactions

This pinacol ester is a key reagent in palladium-catalysed Suzuki-Miyaura cross-coupling reactions. It enables the formation of carbon-carbon bonds by reacting with aryl or vinyl halides and triflates, facilitating the construction of biaryl systems and other complex organic structures.

Medicinal Chemistry Building Block

It is employed as an intermediate in the synthesis of pharmacologically active compounds. The molecule's unique structure allows for the targeted introduction of phenylboronate ester moieties into drug candidates, aiding in the development of novel therapeutics.

Materials Science

This compound can be used in the synthesis of organic electronic materials and polymers. Its participation in cross-coupling reactions allows for the incorporation of specific functional groups, influencing the optical and electronic properties of the resulting materials.

02 /Properties

Molecular weight	247.10
Empirical formula	C13H18BNO3
Assay	97%
Melting point	85-89 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

480425-36-3

MDL number

MFCD03789264

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-(Formylamino)phenylboronic acid pinacol ester used for?

This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the construction of carbon-carbon bonds and in medicinal chemistry for the synthesis of pharmaceutical intermediates.

What is the CAS number and chemical formula for this product?

The CAS number is 480425-36-3, and the chemical formula is C13H18BNO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2-(Formylamino)phenylboronic acid pinacol ester with a minimum purity of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.

How should this chemical be handled safely?

Safety precautions include wearing eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Ensure adequate ventilation and avoid contact with skin and eyes.

Is this chemical a controlled substance?

The provided data does not indicate that 2-(Formylamino)phenylboronic acid pinacol ester is a controlled substance.

How is this product packed, shipped, and exported?

Products are carefully packed to ensure stability during transit and are available for global export by Tech Serve Solutions, adhering to international shipping regulations for chemicals.

How can I request a quote or sample?

To request a quote or a sample, please use the contact form on our website or contact our sales department directly, referencing the product name and CAS number.