2-Fluoro-6-(trifluoromethyl)aniline
2-Fluoro-6-(trifluoromethyl)aniline (CAS: 144851-61-6), with the molecular formula FC6H3(CF3)NH2 and a molecular weight of 179.11 g/mol, is a fluorinated aromatic amine. This compound serves as a valuable building block in organic synthesis. Its structure, featuring both a fluorine atom and a trifluoromethyl group on the aniline ring, makes it useful for introducing specific functionalities into more complex molecules, particularly in the development of pharmaceuticals and agrochemicals.
- IUPAC
- 2-Amino-3-fluorobenzotrifluoride,α,α,α,6-Tetrafluoro-o-toluidine
- Synonyms
- 2-Amino-3-fluorobenzotrifluorideα,α,α,6-Tetrafluoro-o-toluidine
Pharmaceutical Intermediate
This compound is employed as a key intermediate in the synthesis of various pharmaceutical agents. Its fluorinated structure can impart desirable pharmacokinetic properties to drug candidates, such as enhanced metabolic stability and lipophilicity.
Agrochemical Synthesis
It acts as a building block for the development of novel agrochemicals, including herbicides, insecticides, and fungicides. The presence of fluorine and trifluoromethyl groups can influence the biological activity and environmental persistence of these agents.
Materials Science
2-Fluoro-6-(trifluoromethyl)aniline can be utilised in the synthesis of specialty polymers and advanced materials. Its unique electronic and steric properties may contribute to improved material performance characteristics.
Research and Development
As a versatile fluorinated building block, it is frequently used in academic and industrial research laboratories for exploring new chemical pathways and discovering novel compounds with potential applications.
| Molecular weight | 179.11 |
|---|---|
| Linear formula | FC6H3(CF3)NH2 |
| Assay | 98% |
| Boiling point | 155 °C(lit.) |
| Density | 1.388 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.462(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 53 °C / 127.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22-36/37/38 |
| Safety statements (S) | 16-26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-6-(trifluoromethyl)aniline used for?
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2-Fluoro-6-(trifluoromethyl)aniline is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials. It is also widely utilised in research and development settings.
What is the CAS number and molecular formula for 2-Fluoro-6-(trifluoromethyl)aniline?
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The CAS number for 2-Fluoro-6-(trifluoromethyl)aniline is 144851-61-6, and its molecular formula is FC6H3(CF3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-6-(trifluoromethyl)aniline with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How is 2-Fluoro-6-(trifluoromethyl)aniline classified for transport?
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2-Fluoro-6-(trifluoromethyl)aniline is classified as UN 1993, Class 3, Packing Group III, indicating it is a flammable liquid.
What are the main safety hazards associated with this chemical?
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This compound is classified as flammable (H226) and is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
How can I request a quote or sample?
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To request a quote or a sample of 2-Fluoro-6-(trifluoromethyl)aniline, please contact our sales department through the website or by phone, providing your contact details and the quantity required.
Is this chemical packed and exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 2-Fluoro-6-(trifluoromethyl)aniline. It is carefully packed according to transport regulations.
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