2′-Deoxycytidine
2′-Deoxycytidine (CAS 951-77-9), a deoxynucleoside with the formula C9H13N3O4 and molecular weight 227.22, is a fundamental building block in DNA synthesis. It serves as a substrate for DNA polymerases and reverse transcriptases after phosphorylation to dCTP. It is also involved in the enzymatic conversion to 2′-deoxyuridine and the phosphorylation to dCMP.
- IUPAC
- Cytosine deoxyriboside
- Synonyms
- Cytosine deoxyriboside
DNA Synthesis
As a precursor to dCTP, 2′-Deoxycytidine is a vital substrate for various DNA polymerases and reverse transcriptases, enabling the synthesis of DNA strands.
Enzymatic Conversion
This nucleoside acts as a substrate for deoxycytidine deaminase, an enzyme that facilitates its conversion into 2′-deoxyuridine.
Nucleotide Formation
2′-Deoxycytidine is phosphorylated by deoxycytidine kinase (DCK) to form the nucleotide dCMP, a crucial step in nucleotide metabolism.
| Molecular weight | 227.22 |
|---|---|
| Empirical formula | C9H13N3O4 |
| Assay | ≥99% (HPLC) |
| Application | 2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2′-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. 2′-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Deoxycytidine used for?
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2′-Deoxycytidine is used in DNA synthesis as a substrate for DNA polymerases and reverse transcriptases after its conversion to dCTP. It is also involved in enzymatic conversions to other nucleosides and nucleotides, such as 2′-deoxyuridine and dCMP.
What is the CAS number and molecular formula for 2′-Deoxycytidine?
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The CAS number for 2′-Deoxycytidine is 951-77-9, and its molecular formula is C9H13N3O4.
What grade and purity does Tech Serve Solutions supply for 2′-Deoxycytidine?
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Tech Serve Solutions supplies 2′-Deoxycytidine with a minimum purity of ≥99% as determined by HPLC. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
How should 2′-Deoxycytidine be handled safely?
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Handle 2′-Deoxycytidine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is necessary. Refer to the safety data sheet for detailed handling instructions. The product has a WGK Germany rating of 3.
Is 2′-Deoxycytidine a controlled substance?
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The provided data does not indicate that 2′-Deoxycytidine (CAS 951-77-9) is a controlled or scheduled substance.
How is 2′-Deoxycytidine packed, shipped, and exported?
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Tech Serve Solutions ensures that 2′-Deoxycytidine is packed securely for safe transit. We are experienced global suppliers and exporters of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for 2′-Deoxycytidine?
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To request a sample or a quote for 2′-Deoxycytidine, please contact our sales department through the website or via email, providing your specific requirements.
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