2-Chloroquinoxaline
2-Chloroquinoxaline (CAS: 1448-87-9, Formula: C8H5ClN2) is a halogenated heterocyclic organic compound with a molecular weight of 164.59 g/mol. Available at a purity of 98%, it serves as a versatile building block in chemical synthesis. Its applications span research into solvent effects on hydrolysis and the creation of novel quinoxaline derivatives, making it a valuable reagent for synthetic chemists.

Study of Hydrolysis Mechanisms
2-Chloroquinoxaline is utilised in research to investigate the impact of various solvent systems, such as aqueous-organic mixtures containing acetonitrile and dimethyl sulfoxide, on its hydrolysis kinetics.
Synthesis of Quinoxaline Derivatives
This compound acts as a key intermediate in the synthesis of more complex quinoxaline structures, exemplified by its use in preparing 2-(3-butynyl-2-methyl-2-ol)quinoxaline.
Reagent in Organic Synthesis
2-Chloroquinoxaline functions as a reagent in the preparation of functionalised molecules, including the synthesis of chloroquinoxaline sulfamide.
| Molecular weight | 164.59 |
|---|---|
| Empirical formula | C8H5ClN2 |
| Assay | 98% |
| Boiling point | 100 °C/1.4 mmHg(lit.) |
| Application | 2-Chloroquinoxaline (QCI) was used to study the effect of solvent on hydrolysis of QCI in aqueous–organic solvent mixtures with acetonitrile and dimethylesulphoxide1. It was used in the synthesis of 2-(3-butynyl-2-methyl-2-ol) quinoxaline2.It was used as reagent in the synthesis of chloroquinoxaline sulfamide1. |
| Melting point | 47-50 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloroquinoxaline used for?
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2-Chloroquinoxaline is used as a building block in chemical synthesis, for studying hydrolysis mechanisms, and in the preparation of other quinoxaline derivatives such as chloroquinoxaline sulfamide.
What are the CAS number and molecular formula for 2-Chloroquinoxaline?
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The CAS number for 2-Chloroquinoxaline is 1448-87-9, and its molecular formula is C8H5ClN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloroquinoxaline with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and laboratory use.
How should 2-Chloroquinoxaline be handled safely?
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2-Chloroquinoxaline is classified as toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, face shields, and gloves, in a well-ventilated area. Avoid dust formation and inhalation.
Is 2-Chloroquinoxaline a controlled substance?
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The provided data does not indicate that 2-Chloroquinoxaline is a controlled substance.
How is 2-Chloroquinoxaline packed and exported?
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2-Chloroquinoxaline is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 2-Chloroquinoxaline?
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To request a sample or a quotation for 2-Chloroquinoxaline, please contact our sales team through the website or by phone.
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