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2-Chloroquinoxaline

CAS 1448-87-9C8H5ClN2Chemical Synthesis

2-Chloroquinoxaline (CAS: 1448-87-9, Formula: C8H5ClN2) is a halogenated heterocyclic organic compound with a molecular weight of 164.59 g/mol. Available at a purity of 98%, it serves as a versatile building block in chemical synthesis. Its applications span research into solvent effects on hydrolysis and the creation of novel quinoxaline derivatives, making it a valuable reagent for synthetic chemists.

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2-Chloroquinoxaline (C8H5ClN2) — chemical structure, CAS 1448-87-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisHalogenated HeterocyclesHeterocyclic Building BlocksQuinoxalines
01 /Applications

Study of Hydrolysis Mechanisms

2-Chloroquinoxaline is utilised in research to investigate the impact of various solvent systems, such as aqueous-organic mixtures containing acetonitrile and dimethyl sulfoxide, on its hydrolysis kinetics.

Synthesis of Quinoxaline Derivatives

This compound acts as a key intermediate in the synthesis of more complex quinoxaline structures, exemplified by its use in preparing 2-(3-butynyl-2-methyl-2-ol)quinoxaline.

Reagent in Organic Synthesis

2-Chloroquinoxaline functions as a reagent in the preparation of functionalised molecules, including the synthesis of chloroquinoxaline sulfamide.

02 /Properties
Molecular weight164.59
Empirical formulaC8H5ClN2
Assay98%
Boiling point100 °C/1.4 mmHg(lit.)
Application2-Chloroquinoxaline (QCI) was used to study the effect of solvent on hydrolysis of QCI in aqueous–organic solvent mixtures with acetonitrile and dimethylesulphoxide1. It was used in the synthesis of 2-(3-butynyl-2-methyl-2-ol) quinoxaline2.It was used as reagent in the synthesis of chloroquinoxaline sulfamide1.
Melting point47-50 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P301IF SWALLOWED
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1448-87-9
MDL number
MFCD00043907
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Chloroquinoxaline used for?

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2-Chloroquinoxaline is used as a building block in chemical synthesis, for studying hydrolysis mechanisms, and in the preparation of other quinoxaline derivatives such as chloroquinoxaline sulfamide.

What are the CAS number and molecular formula for 2-Chloroquinoxaline?

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The CAS number for 2-Chloroquinoxaline is 1448-87-9, and its molecular formula is C8H5ClN2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Chloroquinoxaline with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and laboratory use.

How should 2-Chloroquinoxaline be handled safely?

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2-Chloroquinoxaline is classified as toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, face shields, and gloves, in a well-ventilated area. Avoid dust formation and inhalation.

Is 2-Chloroquinoxaline a controlled substance?

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The provided data does not indicate that 2-Chloroquinoxaline is a controlled substance.

How is 2-Chloroquinoxaline packed and exported?

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2-Chloroquinoxaline is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.

How can I request a sample or quote for 2-Chloroquinoxaline?

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To request a sample or a quotation for 2-Chloroquinoxaline, please contact our sales team through the website or by phone.

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