(±)-2-Chlorophenylglycine
(±)-2-Chlorophenylglycine (CAS: 88744-36-9) is a chiral alpha-amino acid derivative with the molecular formula C8H8ClNO2 and a molecular weight of 185.61 g/mol. This compound serves as a valuable building block in organic synthesis, particularly within chemical biology and peptide chemistry. Its structure, featuring a chlorinated phenyl ring, makes it a useful intermediate for creating novel molecules with specific biological or chemical properties, often employed in the development of unnatural amino acid derivatives.
- IUPAC
- (±)-α-Amino-2-chlorophenylacetic acid

Chemical Synthesis Intermediate
Used as a precursor or building block in complex organic synthesis pathways. Its unique structure allows for the introduction of a chlorinated phenylglycine moiety into larger molecules.
Peptide Chemistry
Incorporated into peptide chains as an unnatural amino acid to explore modified biological activities or structural properties. Useful in research for designing novel peptides.
Chemical Biology Research
Applied in studies investigating molecular interactions and biological pathways. Its chlorinated phenyl group can influence binding affinities and pharmacological profiles.
Development of Unnatural Amino Acids
Serves as a starting material for the synthesis of various unnatural amino acid derivatives, expanding the toolkit for medicinal chemistry and drug discovery.
| Molecular weight | 185.61 |
|---|---|
| Empirical formula | C8H8ClNO2 |
| Assay | ≥98.0% (TLC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-2-Chlorophenylglycine used for?
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(±)-2-Chlorophenylglycine is primarily used as an intermediate in chemical synthesis, particularly in peptide chemistry and the development of unnatural amino acid derivatives for chemical biology research.
What is the CAS number and molecular formula for (±)-2-Chlorophenylglycine?
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The CAS number is 88744-36-9 and the empirical formula (Hill notation) is C8H8ClNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (±)-2-Chlorophenylglycine with an assay of ≥98.0% as determined by TLC. This product is intended for research and technical use; it is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should (±)-2-Chlorophenylglycine be handled?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure good ventilation in the work area, as it may cause respiratory irritation (H335), skin irritation (H315), and serious eye irritation (H319).
Is (±)-2-Chlorophenylglycine a controlled substance?
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The provided data does not indicate that (±)-2-Chlorophenylglycine is a controlled substance.
How is this chemical packaged and exported?
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Products are carefully packaged according to industry standards to ensure integrity during transit. Tech Serve Solutions is an experienced global exporter of fine chemicals.
How can I request a sample or quote for (±)-2-Chlorophenylglycine?
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To request a sample or a quotation, please use the contact form on our website or contact our sales department directly with your inquiry.
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