2-Chloronicotinamide
2-Chloronicotinamide (CAS: 10366-35-5), with the molecular formula C6H5ClN2O and a molecular weight of 156.57 g/mol, is a halogenated heterocyclic compound. It serves as a valuable building block in organic synthesis. This chemical is primarily utilised in the development of novel compounds, including pyrrolopyridines and thiol ester derivatives, playing a role in chemical research and development.
Synthesis of Pyrrolopyridines
2-Chloronicotinamide is employed as a key intermediate in the synthesis of pyrrolopyridine structures. This application is crucial in the discovery of new chemical entities within research laboratories.
Thiol Ester Derivative Formation
This compound facilitates the creation of thiol ester derivatives, specifically starting from 2-mercaptonicotinamide. This process is significant in organic chemistry for creating complex molecular frameworks.
Heterocyclic Chemistry Building Block
As a member of the halogenated heterocycles family, 2-Chloronicotinamide acts as a versatile building block. It enables chemists to introduce specific functional groups and structural motifs into target molecules.
| Molecular weight | 156.57 |
|---|---|
| Empirical formula | C6H5ClN2O |
| Assay | 98% |
| Application | 2-Chloronicotinamide was used in the synthesis of pyrrolopyridines1 and thiol ester derived from 2-mecaptonicotinamide2. |
| Melting point | 164-167 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloronicotinamide used for?
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2-Chloronicotinamide is primarily used as a building block in organic synthesis, particularly for creating pyrrolopyridines and thiol ester derivatives. It is a valuable intermediate in chemical research and development.
What is the CAS number and formula for 2-Chloronicotinamide?
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The CAS number for 2-Chloronicotinamide is 10366-35-5, and its molecular formula is C6H5ClN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloronicotinamide with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Chloronicotinamide be handled safely?
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2-Chloronicotinamide may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is advised to wear Eyeshields, Gloves, and a dust mask type N95 (US), and handle in a well-ventilated area. Refer to the Safety Data Sheet for full details.
Is 2-Chloronicotinamide packed and shipped by Tech Serve Solutions?
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Yes, Tech Serve Solutions, a specialist global supplier and exporter, provides 2-Chloronicotinamide. We ensure careful packaging and efficient export services.
How can I request a quote or sample for 2-Chloronicotinamide?
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To request a quote or sample for 2-Chloronicotinamide, please use the contact form on our website or reach out to our sales team directly.
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