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2-(Chloromethyl)benzimidazole

CAS 4857-04-9C8H7ClN2Chemical Synthesis

2-(Chloromethyl)benzimidazole (CAS 4857-04-9, C8H7ClN2) is a heterocyclic organic compound with a molecular weight of 166.61 g/mol. It is characterised by a benzimidazole core with a chloromethyl substituent. This compound serves as a versatile intermediate in organic synthesis, particularly for constructing more complex heterocyclic structures relevant in pharmaceutical research and materials science. Its reactivity makes it a valuable building block.

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2-(Chloromethyl)benzimidazole (C8H7ClN2) — chemical structure, CAS 4857-04-9; Chemistry, fine chemical supplied by Tech Serve Solutions
BenzimidazolesBuilding BlocksChemical SynthesisHalogenated HeterocyclesHeterocyclic Building Blocks
01 /Applications

Organic Synthesis Intermediate

Used as a key building block in the synthesis of diverse organic molecules. The chloromethyl group allows for facile nucleophilic substitution reactions, enabling the introduction of the benzimidazole moiety into various target structures.

Pharmaceutical Research

Employed in the development of potential drug candidates. The benzimidazole scaffold is present in numerous biologically active compounds, and this derivative facilitates the exploration of new therapeutic agents.

Heterocyclic Chemistry

A valuable reagent for creating complex heterocyclic systems. It is particularly useful in the preparation of fused ring systems and substituted benzimidazoles.

02 /Properties
Molecular weight166.61
Empirical formulaC8H7ClN2
Assay96%
Melting point146-148 °C (dec.)(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
4857-04-9
MDL number
MFCD00005602
PubChem substance
24892767
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-(Chloromethyl)benzimidazole primarily used for?

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2-(Chloromethyl)benzimidazole is primarily used as a versatile intermediate in organic synthesis, particularly for constructing complex heterocyclic structures in pharmaceutical research and materials science.

What are the CAS number and molecular formula for 2-(Chloromethyl)benzimidazole?

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The CAS number for 2-(Chloromethyl)benzimidazole is 4857-04-9, and its molecular formula is C8H7ClN2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-(Chloromethyl)benzimidazole with an assay of 96%. This product is suitable for research and technical applications; TSS does not represent it as USP, BP, or EP grade.

How should 2-(Chloromethyl)benzimidazole be handled safely?

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Handle 2-(Chloromethyl)benzimidazole with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation, as it is harmful if swallowed and causes skin, eye, and respiratory irritation (H302-H315-H319-H335).

Is 2-(Chloromethyl)benzimidazole available for export?

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Yes, Tech Serve Solutions, a global supplier and exporter since 1998, can fulfil export requirements for 2-(Chloromethyl)benzimidazole worldwide.

How can I request a sample or quote for 2-(Chloromethyl)benzimidazole?

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To request a sample or quote for 2-(Chloromethyl)benzimidazole, please contact our sales team through the website or provide your details via the online inquiry form.

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