2-Chloroacetophenone
2-Chloroacetophenone (CAS: 532-27-4), with the molecular formula C₆H₅COCH₂Cl and a molecular weight of 154.59 g/mol, is a halogenated ketone. It serves as a valuable intermediate in organic synthesis, particularly in the preparation of various heterocyclic compounds and pharmaceuticals. Its reactivity also lends itself to applications in chemical research as a building block for more complex molecules.
- IUPAC
- ω-Chloroacetophenone,Phenacyl chloride
- Synonyms
- Phenacyl chlorideω-Chloroacetophenone
Organic Synthesis Intermediate
2-Chloroacetophenone is frequently employed as a key building block in the synthesis of diverse organic compounds. Its functional groups allow for a range of chemical transformations, making it useful in multi-step synthetic pathways.
Pharmaceutical Research
This compound finds application in the research and development of new pharmaceutical agents. It can be incorporated into the structure of potential drug candidates, leveraging its chemical properties for biological activity.
Chemical Research Reagent
As a readily available reagent, 2-Chloroacetophenone is used in academic and industrial laboratories for exploring novel chemical reactions and developing new synthetic methodologies.
| Molecular weight | 154.59 |
|---|---|
| Linear formula | C6H5COCH2Cl |
| Assay | ≥98.0% (GC) |
| Grade | purum |
| Boiling point | 244-245 °C(lit.) |
| Density | 1.324 g/mL at 25 °C(lit.) |
| Melting point | 53-56 °C54-56 °C(lit.) |
Hazard statements
- H300Fatal if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H318Causes serious eye damage
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1697 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PTPN6(5777) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloroacetophenone used for?
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2-Chloroacetophenone is primarily used as an intermediate in organic synthesis, a building block in chemical research, and in the development of pharmaceutical agents.
What is the CAS number and chemical formula for 2-Chloroacetophenone?
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The CAS number for 2-Chloroacetophenone is 532-27-4, and its linear formula is C₆H₅COCH₂Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloroacetophenone at a purum grade, with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should 2-Chloroacetophenone be handled safely?
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2-Chloroacetophenone is a dangerous substance. Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. It is toxic if swallowed, toxic in contact with skin, toxic if inhaled, causes skin irritation, causes serious eye damage, and may cause respiratory irritation and allergy or asthma symptoms or breathing difficulties if inhaled. Always consult the Safety Data Sheet before use.
How is 2-Chloroacetophenone packed, shipped, and exported?
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2-Chloroacetophenone is packed according to industry standards for hazardous chemicals and is shipped and exported globally by Tech Serve Solutions, adhering to all relevant regulations for UN 1697, 6.1 / PGII.
How can I request a sample or quote for 2-Chloroacetophenone?
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To request a sample or a quotation for 2-Chloroacetophenone, please contact our sales team through the website or by phone.
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