2-Chloro-N-methoxy-N-methylacetamide
2-Chloro-N-methoxy-N-methylacetamide (CAS: 67442-07-3) is an organic compound with the linear formula ClCH 2 CON(OCH 3 )CH 3 and a molecular weight of 137.56 g/mol. As a versatile chemical building block, it finds utility in organic synthesis. Its structure, featuring a chloroacetamide moiety and a Weinreb amide group, makes it a valuable intermediate for constructing more complex molecules in research and development settings.

Organic Synthesis Intermediate
This compound serves as a key intermediate in the synthesis of various organic molecules. The presence of both an electrophilic chloroacetyl group and a Weinreb amide allows for diverse synthetic transformations.
Pharmaceutical Research
It can be employed in the development pathways for novel pharmaceutical agents. Its specific functionalities enable targeted modifications in the creation of potential drug candidates.
Fine Chemical Manufacturing
Utilised in the production of fine chemicals, its reactivity profile is suitable for bespoke chemical manufacturing processes requiring specific structural motifs.
| Molecular weight | 137.56 |
|---|---|
| Linear formula | ClCH2CON(OCH3)CH3 |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Melting point | 39-41 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 23-26-27-28-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-N-methoxy-N-methylacetamide used for?
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2-Chloro-N-methoxy-N-methylacetamide is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals and fine chemicals.
What is the CAS number and chemical formula for this compound?
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The CAS number is 67442-07-3 and the linear chemical formula is ClCH 2 CON(OCH 3 )CH 3 .
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-N-methoxy-N-methylacetamide with an assay of 98%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Chloro-N-methoxy-N-methylacetamide be handled safely?
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Handling requires caution due to hazards H302, H312, and H332 (harmful if swallowed, in contact with skin, or if inhaled). Use appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Work in a well-ventilated area.
How is this chemical packed and shipped?
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This chemical is packed and exported by Tech Serve Solutions adhering to international shipping regulations for chemical compounds.
How can I request a sample or quote for 2-Chloro-N-methoxy-N-methylacetamide?
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To request a sample or a quote, please contact our sales team through the website or by direct inquiry, providing your contact details and requirements.
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