2-Bromobutyryl bromide
2-Bromobutyryl bromide (CAS 26074-52-2), with the linear formula CH3CH2CHBrCOBr and a molecular weight of 229.90 g/mol, is a reactive acid halide. It serves as a valuable building block in organic synthesis. Its primary applications include its use in the preparation of specialised amides, ethyl keten, and bifunctional initiators for polymerisation processes, enabling the creation of advanced materials.

Synthesis of Complex Organic Molecules
2-Bromobutyryl bromide is employed in the synthesis of intricate organic compounds. For instance, it has been utilised in the preparation of specific amides, contributing to the construction of complex molecular architectures.
Preparation of Ethyl Keten
This acid halide is a precursor in the formation of ethyl keten, a reactive intermediate with applications in various organic transformations and synthetic pathways.
Development of Polymerisation Initiators
2-Bromobutyryl bromide facilitates the creation of bifunctional initiators. These specialised initiators are capable of polymerising various monomers, offering control over polymer properties and structure.
| Molecular weight | 229.90 |
|---|---|
| Linear formula | CH3CH2CHBrCOBr |
| Assay | ≥95% (AT) |
| Boiling point | 142-144 °C(lit.) |
| Density | 1.9 g/mL at 20 °C1.905 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.51n20/D 1.512(lit.) |
| Application | 2-Bromobutyryl bromide was used in the synthesis of 2-bromo-N-[(S)-1-phenylethyl]-N-[2-(phenylthio)ethenyl]butanamide1 and ethylketen2. It was used in preparation of bifunctional initiators capable of polymerizing monomers3. |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromobutyryl bromide used for?
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2-Bromobutyryl bromide is used as a building block in organic synthesis, including the preparation of specific amides, ethyl keten, and bifunctional polymerisation initiators.
What is the CAS number and chemical formula for 2-Bromobutyryl bromide?
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The CAS number is 26074-52-2, and the linear formula is CH3CH2CHBrCOBr.
What grade and purity does Tech Serve Solutions supply for 2-Bromobutyryl bromide?
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Tech Serve Solutions supplies 2-Bromobutyryl bromide with an assay of ≥95% (AT). We do not represent this product as USP, BP, or EP grade.
How should 2-Bromobutyryl bromide be handled safely?
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2-Bromobutyryl bromide is corrosive and can cause severe skin burns and eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including gloves, eye protection (goggles and face shield), and respiratory protection. Ensure adequate ventilation.
Is 2-Bromobutyryl bromide exported or shipped by TSS?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Bromobutyryl bromide.
How can I request a sample or quote for 2-Bromobutyryl bromide?
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Please contact our sales team directly to request a sample or a quote for 2-Bromobutyryl bromide.
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