2-Bromo-5-nitropyridine
2-Bromo-5-nitropyridine (CAS: 4487-59-6), a vital organic compound with the formula C5H3BrN2O2, possesses a molecular weight of 202.99 g/mol. This halogenated pyridine derivative serves as a key intermediate in complex chemical syntheses. Its structure, featuring both a bromine atom and a nitro group on the pyridine ring, offers versatile reactivity for constructing more elaborate molecules, particularly in the pharmaceutical and agrochemical sectors. Available from TSS.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs). The bromo- and nitro- functionalities allow for diverse coupling and substitution reactions to build complex drug scaffolds.
Agrochemical Development
Serves as a building block for novel pesticides and herbicides. Its heterocyclic nature is often incorporated into molecules designed for targeted biological activity in agriculture.
Organic Synthesis Reagent
A versatile reagent for introducing the 5-nitropyridin-2-yl moiety into organic molecules. It is employed in various coupling reactions, such as Suzuki and Stille couplings, and nucleophilic aromatic substitutions.
Material Science Research
Can be incorporated into the design of functional organic materials due to its electron-deficient pyridine ring and reactive sites.
| Molecular weight | 202.99 |
|---|---|
| Empirical formula | C5H3BrN2O2 |
| Assay | 99% |
| Boiling point | 145-147 °C/10 mmHg(lit.) |
| Melting point | 139-141 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-5-nitropyridine used for?
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2-Bromo-5-nitropyridine (CAS: 4487-59-6) is primarily used as an intermediate in organic synthesis, particularly for pharmaceuticals and agrochemicals, owing to its reactive bromo and nitro functionalities.
What are the CAS number and formula for 2-Bromo-5-nitropyridine?
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The CAS number for 2-Bromo-5-nitropyridine is 4487-59-6, and its empirical formula is C5H3BrN2O2.
What grade and purity does Tech Serve Solutions supply for 2-Bromo-5-nitropyridine?
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Tech Serve Solutions supplies 2-Bromo-5-nitropyridine with a minimum purity of 99% (Assay). This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Bromo-5-nitropyridine be handled safely?
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2-Bromo-5-nitropyridine is classified as Danger with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate PPE including a dust mask (N95), eyeshields, face shields, and gloves in a well-ventilated area.
Is 2-Bromo-5-nitropyridine a controlled substance?
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The provided data does not indicate that 2-Bromo-5-nitropyridine is a controlled substance.
How is 2-Bromo-5-nitropyridine packed and shipped?
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2-Bromo-5-nitropyridine is packed according to industry standards for chemical safety and stability, suitable for export. Specific packaging details will be provided with your order confirmation.
How can I request a quote or sample of 2-Bromo-5-nitropyridine?
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To request a quote or sample of 2-Bromo-5-nitropyridine, please contact our sales department through the TSS website or by phone, providing your specific requirements.
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