2-Bromo-4-(trifluoromethoxy)aniline
2-Bromo-4-(trifluoromethoxy)aniline (CAS: 175278-17-8), with the molecular formula BrC6H3(OCF3)NH2 and a molecular weight of 256.02 g/mol, is a fluorinated aromatic amine. This compound serves as a valuable building block in organic synthesis, primarily utilised in the development of complex molecules within the pharmaceutical and agrochemical industries. Its structure allows for diverse chemical transformations, making it a key intermediate in research and development.

Pharmaceutical Intermediate
Used in the synthesis of novel drug candidates. The bromo and trifluoromethoxy substituents offer specific reactivity for building complex heterocyclic systems found in many active pharmaceutical ingredients.
Agrochemical Synthesis
Acts as a precursor for the development of new pesticides and herbicides. Its unique halogenation and ether groups can contribute to the efficacy and targeted action of agrochemical products.
Organic Building Block
A versatile reagent in general organic synthesis for introducing fluorinated aniline moieties. It is employed in the creation of diverse organic compounds for research purposes.
| Molecular weight | 256.02 |
|---|---|
| Linear formula | BrC6H3(OCF3)NH2 |
| Assay | 98% |
| Boiling point | 209 °C(lit.) |
| Density | 1.693 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-4-(trifluoromethoxy)aniline used for?
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2-Bromo-4-(trifluoromethoxy)aniline is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical and agrochemical compounds. It serves as a key intermediate for creating more complex molecules.
What are the CAS number and molecular formula for 2-Bromo-4-(trifluoromethoxy)aniline?
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The CAS number for 2-Bromo-4-(trifluoromethoxy)aniline is 175278-17-8, and its molecular formula is BrC6H3(OCF3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-4-(trifluoromethoxy)aniline with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 2-Bromo-4-(trifluoromethoxy)aniline be handled safely?
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This compound is classified as a warning substance with hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields and suitable gloves, should be worn. Ensure adequate ventilation or use a respirator when handling.
How is 2-Bromo-4-(trifluoromethoxy)aniline packaged and exported?
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2-Bromo-4-(trifluoromethoxy)aniline is carefully packaged to ensure stability during transport and is exported globally by Tech Serve Solutions, adhering to all necessary shipping regulations for chemical substances.
How can I request a sample or a quote for 2-Bromo-4-(trifluoromethoxy)aniline?
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To request a sample or obtain a quotation for 2-Bromo-4-(trifluoromethoxy)aniline, please contact our sales department via the website or direct email, providing your specific requirements.
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