2-Bromo-4-fluoropyridine
2-Bromo-4-fluoropyridine (CAS: 357927-50-5) is a pyridine derivative with the molecular formula C5H3BrFN and a molecular weight of 175.99 g/mol. This halogenated and fluorinated heterocyclic compound serves as a valuable building block in organic synthesis. It is primarily utilised in the research and development of novel chemical entities and complex molecular structures, particularly within the pharmaceutical and agrochemical sectors. Its specific substitution pattern makes it an attractive intermediate for creating diverse chemical libraries.
- IUPAC
- 4-Fluoro-2-bromopyridine
- Synonyms
- 4-Fluoro-2-bromopyridine
Chemical Synthesis Intermediate
2-Bromo-4-fluoropyridine is employed as a versatile intermediate in the synthesis of more complex organic molecules. Its reactive bromine atom and the presence of fluorine on the pyridine ring offer pathways for various coupling and substitution reactions.
Pharmaceutical Research
This compound is used in the development of new drug candidates. The fluoropyridine moiety is found in several biologically active molecules, making 2-Bromo-4-fluoropyridine a useful starting material for medicinal chemistry efforts.
Agrochemical Development
In the agrochemical industry, 2-Bromo-4-fluoropyridine can be utilised as a building block for the synthesis of new pesticides, herbicides, and fungicides. The incorporation of fluorine often enhances the efficacy and metabolic stability of agrochemical agents.
Materials Science
As a functionalised heterocycle, it may find applications in the development of advanced materials, including organic electronics and specialised polymers, where its electronic and structural properties can be exploited.
| Molecular weight | 175.99 |
|---|---|
| Empirical formula | C5H3BrFN |
| Assay | 96% |
| Density | 1.699 g/mL at 25 °C |
| Refractive index | n20/D 1.537 |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | 76 °C / 168.8 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-4-fluoropyridine used for?
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2-Bromo-4-fluoropyridine is primarily used as a building block and intermediate in organic synthesis, particularly in the research and development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 2-Bromo-4-fluoropyridine?
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The CAS number is 357927-50-5, and the molecular formula is C5H3BrFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-4-fluoropyridine with an assay of 96%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Bromo-4-fluoropyridine be handled safely?
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2-Bromo-4-fluoropyridine is classified as Danger, harmful if swallowed (H302) and causes serious eye damage (H318). Handle with appropriate personal protective equipment, including gloves and eye protection, and avoid ingestion. Ensure good ventilation.
How is 2-Bromo-4-fluoropyridine packed and exported?
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2-Bromo-4-fluoropyridine is packed in compliance with transport regulations, including NA 1993, PGIII. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a quote or sample?
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To request a quote or sample of 2-Bromo-4-fluoropyridine, please contact the Tech Serve Solutions sales team through our website or by phone.
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