2-Arachidonyl glycerol
2-Arachidonoylglycerol (CAS: 53847-30-6, C23H38O4, MW: 378.55) is a lipid mediator and endogenous cannabinoid. Supplied as an acetonitrile solution, it is primarily used in scientific research for investigating cell signaling, neurobiology, and pharmacological pathways. This compound plays a crucial role in modulating various physiological processes within the body, making it an important tool for researchers in neuroscience and cell biology.
- IUPAC
- (all-Z)-5,8,11,14-Eicosatetraenoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester,2-Arachidonoylglycerol,2-Monoarachidonoylglycerol,2-AG
- Synonyms
- 2-Arachidonoylglycerol2-Monoarachidonoylglycerol2-AG(all-Z)-5,8,11,14-Eicosatetraenoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester
Neuroscience Research
2-Arachidonoylglycerol serves as a key endocannabinoid, influencing neurotransmission and synaptic plasticity. Its involvement in CB1 and CB2 receptor activation makes it invaluable for studying pain, appetite, and mood regulation.
Cell Signaling Studies
As an endogenous signaling lipid, 2-AG is integral to understanding cellular communication pathways. Researchers utilize it to explore lipid-based signaling cascades affecting various cellular functions.
Pharmacological Investigations
This compound is used to probe the endocannabinoid system's role in disease states and to develop potential therapeutic interventions. Its interactions with enzymes like FAAH are crucial for drug discovery.
Bioactive Molecule Research
2-Arachidonoylglycerol is studied for its broad bioactivity, contributing to a deeper understanding of lipidomics and its impact on biological systems.
| Molecular weight | 378.55 |
|---|---|
| Empirical formula | C23H38O4 |
| Assay | ≥98% (HPLC) |
| Form | acetonitrile solution |
| Concentration | ~10 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 2 °C / 35.6 °F |
| Transport (UN / ADR) | UN 1648 3 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-20/21/22-36 |
| Safety statements (S) | 16-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | 9:1 mixture of 2-AG and 1-AG |
|---|---|
| Drug Control | regulated under CDSA - not available from Canada |
| Shipped In | wet ice |
| Gene Information | human ... FAAH(2166)rat ... Cnr1(25248), Cnr2(57302) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Arachidonoylglycerol used for?
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2-Arachidonoylglycerol is used in scientific research for investigating cell signaling, neurobiology, and pharmacological pathways, particularly within the endocannabinoid system.
What is the CAS number and formula for 2-Arachidonoylglycerol?
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The CAS number for 2-Arachidonoylglycerol is 53847-30-6, and its empirical formula is C23H38O4.
What grade and purity does Tech Serve Solutions supply for 2-Arachidonoylglycerol?
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Tech Serve Solutions supplies 2-Arachidonoylglycerol with an assay of ≥98% by HPLC. It is supplied as an acetonitrile solution and is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for 2-Arachidonoylglycerol?
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2-Arachidonoylglycerol is a flammable liquid and vapour (H225) and is harmful if swallowed or inhaled (H302 + H332). It also causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, away from ignition sources.
How is 2-Arachidonoylglycerol shipped?
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2-Arachidonoylglycerol is shipped in wet ice to maintain its stability during transit.
Is 2-Arachidonoylglycerol a controlled substance?
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Yes, 2-Arachidonoylglycerol is regulated under the CDSA and is not available from Canada.
How can I request a quote or sample of 2-Arachidonoylglycerol?
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To request a quote or sample of 2-Arachidonoylglycerol, please contact our sales department through the website or by phone.
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