2-Amino-6-(trifluoromethyl)pyridine
2-Amino-6-(trifluoromethyl)pyridine (CAS 34486-24-3) is a chemical compound with the formula C6H5F3N2 and a molecular weight of 162.11 g/mol. This pyridine derivative functions as a valuable building block in chemical synthesis. It is primarily utilised as a substrate in the one-pot synthesis of its corresponding 7-aza-indole, showcasing its utility in heterocyclic chemistry and the development of more complex organic molecules.
Synthesis of 7-Aza-indole Derivatives
2-Amino-6-(trifluoromethyl)pyridine serves as a key substrate in a specific one-pot synthetic methodology. This application leads to the formation of 7-aza-indole compounds, which are important structural motifs in various biologically active molecules.
Heterocyclic Building Block
As a functionalised pyridine, this compound is a versatile building block for constructing diverse heterocyclic systems. Its trifluoromethyl group offers unique electronic properties, useful in medicinal chemistry and materials science research.
Chemical Synthesis Intermediate
This chemical is employed as an intermediate in complex organic synthesis pathways. It allows for the introduction of the trifluoromethylpyridine moiety into larger molecular structures, facilitating the creation of novel compounds.
| Molecular weight | 162.11 |
|---|---|
| Empirical formula | C6H5F3N2 |
| Assay | 97% |
| Application | Substrate used in a one-pot synthesis of the corresponding 7-aza-indole.1 |
| Melting point | 85-89 °C |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38-43 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-6-(trifluoromethyl)pyridine primarily used for?
+
2-Amino-6-(trifluoromethyl)pyridine is used as a substrate in the one-pot synthesis of 7-aza-indole compounds and as a versatile building block in organic chemical synthesis.
What is the CAS number and chemical formula for 2-Amino-6-(trifluoromethyl)pyridine?
+
The CAS number is 34486-24-3 and the chemical formula is C6H5F3N2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Amino-6-(trifluoromethyl)pyridine with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Amino-6-(trifluoromethyl)pyridine be handled safely?
+
This compound is classified as acutely toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, should be used. Handle in a well-ventilated area and avoid dust formation.
Is 2-Amino-6-(trifluoromethyl)pyridine supplied internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Amino-6-(trifluoromethyl)pyridine.
How can I request a sample or quote for 2-Amino-6-(trifluoromethyl)pyridine?
+
Please contact our sales team via the website or telephone to request a sample or a quotation for 2-Amino-6-(trifluoromethyl)pyridine.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis