2-Amino-6-chloropurine riboside

CAS 2004-07-1C10H12ClN5O4Chemical Synthesis

2-Amino-6-chloropurine riboside (CAS: 2004-07-1, C10H12ClN5O4) is a purine nucleoside analogue with a molecular weight of 301.69 g/mol. This compound serves as a key building block in organic synthesis. Its primary applications involve its use in the biosynthesis of various prodrug nucleosides and modified purine analogues, contributing to advancements in medicinal chemistry and biochemical research.

IUPAC: (−)-2-Amino-6-chloropurine riboside,6-Chloroguanine riboside

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2-Amino-6-chloropurine riboside (C10H12ClN5O4) — chemical structure, CAS 2004-07-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisBiochemicals and ReagentsChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksNucleoside AnalogsNucleosidesNucleotidesOligonucleotidesPurines More...

01 /Applications

Biosynthesis of Mutagenic Nucleosides

This compound is employed in the synthesis of mutagenic nucleosides. It plays a role in the creation of modified adenosine derivatives used in biochemical studies.

Synthesis of Prodrug Nucleosides

It is utilized in the preparation of prodrug nucleosides, such as 6-deoxyacyclovir. This application is crucial for developing new therapeutic agents.

Preparation of 6-Arylthio Analogues

2-Amino-6-chloropurine riboside is a precursor for synthesising 6-arylthio analogues of purines. These derivatives are valuable in medicinal chemistry research.

Chiral Building Block

As a chiral heterocyclic compound, it functions as a versatile building block in asymmetric synthesis. It enables the construction of complex molecular architectures.

02 /Properties

Molecular weight	301.69
Empirical formula	C10H12ClN5O4
Assay	≥95%
Storage temperature	−20°C
Application	2-Amino-6-chloropurine riboside is used in the biosynthesis of mutagenic and prodrug nucleosides such as 2′-deoxy-2-(p-nitrophenyl)-adenosine and 6-deoxyacyclovir and of 6-arylthio analogues.
Melting point	165-167 °C (dec.)(lit.)

03 /Identifiers & registry

CAS number

2004-07-1

MDL number

MFCD00005735

PubChem substance

24890889

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 2-Amino-6-chloropurine riboside used for?

2-Amino-6-chloropurine riboside is used in the biosynthesis of mutagenic and prodrug nucleosides, such as 2′-deoxy-2-(p-nitrophenyl)-adenosine and 6-deoxyacyclovir, and in the synthesis of 6-arylthio analogues.

What are the CAS number and formula for 2-Amino-6-chloropurine riboside?

The CAS number is 2004-07-1 and the empirical formula is C10H12ClN5O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2-Amino-6-chloropurine riboside with an assay of ≥95%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.

How should 2-Amino-6-chloropurine riboside be handled and stored?

According to safety data, this compound is hazardous. It should be stored at -20°C. Handle with appropriate personal protective equipment in a well-ventilated area.

Is 2-Amino-6-chloropurine riboside a controlled substance?

The provided data does not indicate that 2-Amino-6-chloropurine riboside is a controlled substance.

How is this chemical packed and exported?

Tech Serve Solutions packs and exports chemicals according to international shipping regulations for hazardous materials. Specific packaging details are available upon request.

How can I request a sample or quote for 2-Amino-6-chloropurine riboside?

To request a sample or quote, please contact our sales department via the website or direct email, providing your contact details and required quantity.