2-Amino-5-(trifluoromethyl)pyridine
2-Amino-5-(trifluoromethyl)pyridine (CAS: 74784-70-6; Formula: C6H5F3N2) is a valuable organic compound with a molecular weight of 162.11 g/mol. This pyridine derivative features a trifluoromethyl group, making it a useful building block in organic synthesis. It is frequently employed in the development of novel chemical entities within pharmaceutical and agrochemical research. Available with an assay of 97%, it serves as a reliable reagent for demanding chemical transformations.
Pharmaceutical Intermediate
2-Amino-5-(trifluoromethyl)pyridine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its unique structural features, including the pyridine ring and trifluoromethyl group, allow for the introduction of specific functionalities into drug candidates.
Agrochemical Synthesis
The compound finds application in the development of new agrochemicals, such as herbicides, insecticides, and fungicides. The trifluoromethyl moiety often enhances the biological activity and metabolic stability of the target molecules.
Organic Synthesis Building Block
As a versatile building block, 2-Amino-5-(trifluoromethyl)pyridine is utilised in various organic transformations, including cross-coupling reactions and heterocyclisation, enabling the construction of complex molecular architectures.
Material Science Research
It can be incorporated into the synthesis of functional materials, leveraging the electronic properties conferred by the trifluoromethylpyridine scaffold for applications in areas like organic electronics.
| Molecular weight | 162.11 |
|---|---|
| Empirical formula | C6H5F3N2 |
| Assay | 97% |
| Melting point | 45-49 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-(trifluoromethyl)pyridine used for?
+
2-Amino-5-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical intermediates, agrochemicals, and functional materials.
What is the CAS number and chemical formula for 2-Amino-5-(trifluoromethyl)pyridine?
+
The CAS number is 74784-70-6 and the chemical formula is C6H5F3N2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Amino-5-(trifluoromethyl)pyridine with an assay of 97%. This is a research or technical grade material and is not represented as USP, BP, EP, or any pharmacopoeia standard.
How should 2-Amino-5-(trifluoromethyl)pyridine be handled safely?
+
This compound is classified as Dangerous. It is toxic if swallowed and causes skin and serious eye irritation, with potential respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, should be used. Handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
How is 2-Amino-5-(trifluoromethyl)pyridine typically shipped or exported?
+
2-Amino-5-(trifluoromethyl)pyridine is shipped and exported in compliance with international regulations for hazardous materials. It is assigned UN 2811, Class 6.1, Packing Group III.
How can I request a sample or quote for 2-Amino-5-(trifluoromethyl)pyridine?
+
To request a sample or obtain a quotation, please contact our sales department via the website or by phone, providing the product name and CAS number (74784-70-6).
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis