2-Amino-5-chlorobenzonitrile
2-Amino-5-chlorobenzonitrile (CAS: 5922-60-1) is a vital organic building block with the molecular formula H2NC6H3(Cl)CN and a molecular weight of 152.58 g/mol. This compound serves as a key intermediate in chemical synthesis, particularly for constructing complex heterocyclic systems. It is supplied by Tech Serve Solutions with an assay of 98%, suitable for research and industrial applications. Its unique structure makes it valuable in the development of new chemical entities.
- IUPAC
- 5-Chloroanthranilonitrile

Organic Synthesis Intermediate
2-Amino-5-chlorobenzonitrile is employed as a versatile building block in organic synthesis. Its functional groups allow for diverse chemical transformations, enabling the construction of more complex molecules and heterocyclic frameworks.
Heterocyclic Chemistry
This compound is specifically utilized in the synthesis of heterocyclic compounds. For instance, it has been used in the construction of the 2,2-dioxide-1H-2,1,3-benzothiadiazine ring system, a core structure in various chemical research endeavours.
Pharmaceutical Intermediate Development
As a functionalised aromatic nitrile, 2-Amino-5-chlorobenzonitrile can serve as a precursor or intermediate in the development pathways for novel pharmaceutical agents and active pharmaceutical ingredients.
| Molecular weight | 152.58 |
|---|---|
| Linear formula | H2NC6H3(Cl)CN |
| Assay | 98% |
| Boiling point | 132-135 °C/0.5 mmHg(lit.) |
| Application | 2-Amino-5-chlorobenzonitrile was used to build up the 2,2-dioxide-1H-2,1,3-benzothiadiazine ring system1. |
| Melting point | 96-99 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-chlorobenzonitrile used for?
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2-Amino-5-chlorobenzonitrile is primarily used as a building block in organic synthesis and for the construction of heterocyclic ring systems, such as the 2,2-dioxide-1H-2,1,3-benzothiadiazine system.
What are the CAS number and chemical formula for 2-Amino-5-chlorobenzonitrile?
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The CAS number for 2-Amino-5-chlorobenzonitrile is 5922-60-1, and its linear formula is H2NC6H3(Cl)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-chlorobenzonitrile with a minimum assay of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 2-Amino-5-chlorobenzonitrile be handled?
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2-Amino-5-chlorobenzonitrile is classified with GHS07 symbol and carries a Warning signal word. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, as well as respiratory irritation (H302-H312-H315-H319-H332-H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 2-Amino-5-chlorobenzonitrile typically packed and exported?
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Tech Serve Solutions packs and exports chemicals in compliance with international shipping regulations, ensuring safe transit. Specific packaging details are available upon request for bulk or custom orders.
How can I request a quote or sample of 2-Amino-5-chlorobenzonitrile?
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To request a quote or a sample of 2-Amino-5-chlorobenzonitrile, please contact our sales team through the website or by direct enquiry, providing your specific requirements.
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