2-Amino-5-(4-nitrophenyl)-1,3,4-thiadiazole
2-Amino-5-(4-nitrophenyl)-1,3,4-thiadiazole (CAS: 833-63-6) is a heterocyclic organic compound with the molecular formula C8H6N4O2S. This thiadiazole derivative serves as a valuable building block in chemical synthesis. Its structure, featuring both amino and nitrophenyl functionalities on a thiadiazole core, makes it suitable for various synthetic routes and applications within organic and medicinal chemistry research.
- Synonyms
- 833-63-6, C8H6N4O2S

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of more complex organic molecules. Its functional groups allow for diverse chemical transformations, facilitating the creation of novel compounds.
Heterocyclic Chemistry Research
Serves as a building block for the construction of various heterocyclic systems, particularly those incorporating the 1,3,4-thiadiazole moiety. Research often focuses on exploring its reactivity and incorporation into new chemical entities.
Medicinal Chemistry Exploration
Investigated for its potential in the development of new pharmaceutical agents. The thiadiazole scaffold is present in various biologically active molecules, making this compound a starting point for drug discovery efforts.
| Molecular weight | 222.22 |
|---|---|
| Empirical formula | C8H6N4O2S |
| Melting point | 257-261 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-(4-nitrophenyl)-1,3,4-thiadiazole primarily used for?
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This compound is primarily used as a building block in organic synthesis and heterocyclic chemistry research, with potential applications explored in medicinal chemistry.
What are the CAS number and molecular formula for this chemical?
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The CAS number is 833-63-6 and the molecular formula is C8H6N4O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are available upon request; we do not represent this product as USP, BP, or EP grade.
How should 2-Amino-5-(4-nitrophenyl)-1,3,4-thiadiazole be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Ensure good ventilation. This compound may cause skin irritation, eye irritation, and respiratory irritation (H315, H319, H335).
How is this chemical packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions packs and exports chemicals in compliance with international shipping regulations. Packaging is designed to ensure product integrity and safety during transit.
How can I request a quote or sample for 2-Amino-5-(4-nitrophenyl)-1,3,4-thiadiazole?
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Please contact our sales team via the website or email to request a quote or sample. Provide your contact details and the quantity required.
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