2-Amino-4-chlorobenzoic acid
2-Amino-4-chlorobenzoic acid (CAS: 89-77-0), with the molecular formula H2NC6H3(Cl)CO2H and a molecular weight of 171.58 g/mol, is a crucial intermediate in organic synthesis. This aromatic amino acid derivative is primarily utilised in chemical synthesis and research laboratories. Its structure lends itself to various chemical transformations, making it a valuable building block for more complex molecules in areas like chemical biology and peptide chemistry.
- IUPAC
- 4-Chloroanthranilic acid

Chemical Synthesis Intermediate
2-Amino-4-chlorobenzoic acid serves as a versatile building block in the synthesis of diverse organic compounds. Its reactive amino and carboxylic acid groups, along with the chlorine substituent, allow for a range of derivatisation reactions, facilitating the construction of complex molecular architectures.
Research and Development
This compound is frequently employed in research settings, particularly within chemical biology and medicinal chemistry. It acts as a precursor for developing novel compounds with potential biological activities or as a reagent in exploring new synthetic methodologies.
Peptide Chemistry
As an unnatural amino acid derivative, 2-Amino-4-chlorobenzoic acid can be incorporated into peptide sequences. This allows for the modification of peptide properties, such as stability, conformation, or receptor binding affinity, opening avenues for novel peptide-based therapeutics or research tools.
| Molecular weight | 171.58 |
|---|---|
| Linear formula | H2NC6H3(Cl)CO2H |
| Assay | 98% |
| Melting point | 231-233 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-chlorobenzoic acid used for?
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2-Amino-4-chlorobenzoic acid is primarily used as an intermediate in chemical synthesis, particularly in areas like chemical biology, peptide chemistry, and the development of unnatural amino acid derivatives. It serves as a valuable building block for creating more complex organic molecules.
What are the CAS number and molecular formula for 2-Amino-4-chlorobenzoic acid?
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The CAS number for 2-Amino-4-chlorobenzoic acid is 89-77-0, and its molecular formula is H2NC6H3(Cl)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-4-chlorobenzoic acid with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Amino-4-chlorobenzoic acid be handled safely?
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2-Amino-4-chlorobenzoic acid is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation and avoid breathing dust.
Is 2-Amino-4-chlorobenzoic acid a controlled substance?
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The provided data does not indicate that 2-Amino-4-chlorobenzoic acid is a controlled substance.
How is 2-Amino-4-chlorobenzoic acid packed and shipped?
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Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all necessary regulations for safe transport.
How can I request a quote or sample for 2-Amino-4-chlorobenzoic acid?
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To request a quote or sample, please contact our sales team via the website or direct contact details provided. We are happy to assist with your chemical requirements.
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