2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde
2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde (CAS: 5604-46-6) is a heterocyclic organic compound with the molecular formula C5H3Cl2N3O and a molecular weight of 192.00 g/mol. It serves as a valuable intermediate and building block in organic synthesis. This chemical is particularly employed as a substrate in the preparation of N-terminal surrogates for amino acid and peptide analogues. Its structure lends itself to diverse chemical modifications for research and development purposes.
- Synonyms
- C5H3Cl2N3O

Synthesis of Peptide Analogues
2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde is utilised as a key substrate in the synthesis of N-terminal surrogates. These surrogates are essential for creating modified amino acids and peptide analogues for pharmaceutical research.
Organic Building Block
As a halogenated heterocyclic compound with an aldehyde functionality, it acts as a versatile building block in complex organic synthesis. It enables the construction of novel molecular scaffolds for various chemical applications.
Chemical Research and Development
This compound is frequently used in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities. Its specific structure facilitates targeted derivatisation.
| Molecular weight | 192.00 |
|---|---|
| Empirical formula | C5H3Cl2N3O |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Substrate used in the synthesis of an N-terminal surrogate in amino acid and peptide analogues.1 |
| Melting point | 208-224 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde used for?
+
This compound is primarily used as a substrate in the synthesis of N-terminal surrogates for amino acid and peptide analogues in chemical research and development.
What is the CAS number and molecular formula for 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde?
+
The CAS number is 5604-46-6, and the molecular formula is C5H3Cl2N3O. The empirical formula in Hill notation is C5H3Cl2N3O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde with a minimum assay of 97%. This product is typically for research and technical use and is not supplied as USP, BP, or EP grade.
How should 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde be handled and stored?
+
Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves. It is irritating to the skin, eyes, and respiratory system (H315, H319, H335) and may cause an allergic skin reaction (H317). Store at 2-8°C.
Is 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde a controlled substance?
+
The provided data does not indicate that 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde is a controlled substance.
How is this chemical shipped and exported by TSS?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling the packaging and export of products like 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde according to international regulations.
How can I request a quote or sample?
+
To request a quote or sample for 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde, please contact the TSS sales team via our website or direct contact details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis