2-Acetyl-3-bromothiophene
2-Acetyl-3-bromothiophene (CAS: 42877-08-7) is a halogenated heterocyclic compound with the molecular formula C6H5BrOS and a molecular weight of 205.07 g/mol. This thiophene derivative serves as a valuable building block in organic synthesis. Its structure, featuring both an acetyl group and a bromine atom on the thiophene ring, allows for diverse chemical transformations. It is primarily utilised in research and development for the synthesis of more complex organic molecules.
- IUPAC
- 1-(3-Bromo-2-thienyl)ethanone
- Synonyms
- 1-(3-Bromo-2-thienyl)ethanone

Organic Synthesis Intermediate
2-Acetyl-3-bromothiophene is a key intermediate in the synthesis of novel organic compounds. Its reactive sites enable various coupling reactions and functional group transformations.
Heterocyclic Chemistry Research
This compound is employed in academic and industrial research focused on the development of new thiophene-based molecules with potential applications in materials science and pharmaceuticals.
Building Block for Complex Molecules
The presence of both an acetyl and a bromo substituent makes it a versatile synthon for constructing more elaborate molecular architectures.
| Molecular weight | 205.07 |
|---|---|
| Empirical formula | C6H5BrOS |
| Assay | 97% |
| Refractive index | n20/D 1.612 |
| Melting point | 28-35 °C |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetyl-3-bromothiophene used for?
+
2-Acetyl-3-bromothiophene (CAS: 42877-08-7) is primarily used as a building block in organic synthesis for the creation of more complex heterocyclic compounds, particularly in research and development settings.
What is the CAS number and formula for 2-Acetyl-3-bromothiophene?
+
The CAS number for 2-Acetyl-3-bromothiophene is 42877-08-7, and its empirical formula (Hill notation) is C6H5BrOS.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Acetyl-3-bromothiophene with a minimum assay of 97%. This product is not represented as USP, BP, or EP grade.
How should 2-Acetyl-3-bromothiophene be handled safely?
+
2-Acetyl-3-bromothiophene is classified with Warning signal word and hazards including H302 (Harmful if swallowed), H317 (May cause an allergic skin reaction), and H319 (Causes serious eye irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, faceshields, and gloves. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
Is 2-Acetyl-3-bromothiophene a controlled substance?
+
The provided data does not indicate that 2-Acetyl-3-bromothiophene is a controlled substance.
How is 2-Acetyl-3-bromothiophene packed and shipped?
+
2-Acetyl-3-bromothiophene is packed and shipped according to international regulations for chemical substances. As a global supplier, Tech Serve Solutions ensures compliance with all export and shipping requirements.
How can I request a quote or sample?
+
To request a quote or a sample of 2-Acetyl-3-bromothiophene, please contact our sales department through the website or by calling us directly. Provide your details and the product CAS number (42877-08-7).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis