2-Acetoxyphenylboronic acid pinacol ester
2-Acetoxyphenylboronic acid pinacol ester (CAS 480424-68-8) is a valuable organoboron compound with the linear formula C14H21BO4. Characterised by its pinacol boronate ester moiety, it serves as a key intermediate in organic synthesis, particularly in cross-coupling reactions. Its structure facilitates the introduction of substituted phenyl groups into complex molecules, making it relevant in the development of novel organic materials and pharmaceutical candidates.
- IUPAC
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl acetate
- Synonyms
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl acetate

Organic Synthesis Intermediate
Serves as a crucial building block in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. It is used in the synthesis of complex organic molecules and advanced materials.
Pharmaceutical Research
A versatile reagent for the synthesis of drug candidates and biologically active compounds. Its structure allows for the modification of pharmaceutical scaffolds during lead optimisation.
Materials Science
Utilised in the development of new organic electronic materials, polymers, and functionalised surfaces. The boronate ester group allows for controlled polymerisation and surface modification.
| Molecular weight | 262.11 |
|---|---|
| Linear formula | C6H4OCOCH3BO2C2(CH3)4 |
| Melting point | 47-51 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetoxyphenylboronic acid pinacol ester used for?
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2-Acetoxyphenylboronic acid pinacol ester (CAS 480424-68-8) is primarily used as an intermediate in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in pharmaceutical research and materials science.
What is the CAS number and molecular formula?
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The CAS number for 2-Acetoxyphenylboronic acid pinacol ester is 480424-68-8. Its linear formula is C14H21BO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Acetoxyphenylboronic acid pinacol ester with a purity typically greater than or equal to 97%. This is a research or technical grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations?
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Handle 2-Acetoxyphenylboronic acid pinacol ester with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a flash point of 110 °C (230 °F) and is classified under WGK 2 in Germany.
How is this chemical shipped and exported?
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Tech Serve Solutions expertly packs and exports chemicals globally, adhering to all relevant shipping regulations for international transit. Please contact us for specific export details.
How can I request a sample or quote for 2-Acetoxyphenylboronic acid pinacol ester?
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To request a sample or a quote, please visit the product page on our website and use the 'Request Quote' or 'Sample Request' form, or contact our sales team directly.
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