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2,6-Bis(di-tert-butylphosphinomethyl)pyridine

CAS 338800-13-8C23H43NP2Catalysis & Inorganic

2,6-Bis(di-tert-butylphosphinomethyl)pyridine (CAS: 338800-13-8), with molecular formula C23H43NP2 and a molar mass of 395.54 g/mol, is a speciality phosphine ligand. It is valued for its application in homogeneous catalysis, particularly in cross-coupling reactions. Its bulky tert-butyl groups provide steric control and enhance catalyst stability, making it a key component in advanced chemical synthesis for various research and industrial applications.

Synonyms
C23H43NP2
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2,6-Bis(di-tert-butylphosphinomethyl)pyridine (C23H43NP2) — chemical structure, CAS 338800-13-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisPhosphine CompoundsPhosphine Ligands
01 /Applications

Homogeneous Catalysis

This phosphine ligand serves as a crucial component in homogeneous catalysis, enabling efficient and selective chemical transformations. It is particularly effective in catalysing various cross-coupling reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds.

Organometallic Chemistry

It is employed in organometallic chemistry as a ligand to stabilise metal complexes. The steric bulk of the di-tert-butylphosphinomethyl groups influences the coordination sphere of metal centres, impacting reactivity and selectivity in catalytic cycles.

Chemical Synthesis

Used as a building block or reagent in complex organic synthesis pathways. Its unique structure contributes to controlling reaction outcomes, making it valuable for creating intricate molecular architectures in research and development settings.

02 /Properties
Molecular weight395.54
Empirical formulaC23H43NP2
Melting point116-119 °C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H261In contact with water releases flammable gas
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P231Handle under inert gas
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
  • P422
Flash point67 °C / 152.6 °F
Transport (UN / ADR)UN 2813 4.3 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xi
Risk statements (R)14/15-36/37/38
Safety statements (S)26-36/37/39-43
Supplemental hazardsReacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
338800-13-8
MDL number
MFCD10565623
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,6-Bis(di-tert-butylphosphinomethyl)pyridine used for?

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This compound is primarily used as a bulky phosphine ligand in homogeneous catalysis, particularly for cross-coupling reactions, and in organometallic chemistry for stabilising metal complexes in chemical synthesis.

What is the CAS number and molecular formula for 2,6-Bis(di-tert-butylphosphinomethyl)pyridine?

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The CAS number is 338800-13-8 and the molecular formula is C23H43NP2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2,6-Bis(di-tert-butylphosphinomethyl)pyridine as a research chemical. We do not represent it as USP, BP, EP or any other pharmacopoeia grade.

How should 2,6-Bis(di-tert-butylphosphinomethyl)pyridine be handled and stored?

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This compound is flammable and reacts violently with water (H225, H261). It also causes skin, eye, and respiratory irritation (H315, H319, H335). Store away from water and heat, in a tightly sealed container in a cool, dry, well-ventilated area. Handle under an inert atmosphere (e.g., nitrogen or argon).

Is 2,6-Bis(di-tert-butylphosphinomethyl)pyridine available for export?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,6-Bis(di-tert-butylphosphinomethyl)pyridine, catering to customers worldwide.

How can I request a sample or quote for 2,6-Bis(di-tert-butylphosphinomethyl)pyridine?

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Please contact our sales team via the website or email to request a sample or obtain a quotation for 2,6-Bis(di-tert-butylphosphinomethyl)pyridine.

Need 2,6-Bis(di-tert-butylphosphinomethyl)pyridine in a specific grade or volume?