2,6-Bis(di-tert-butylphosphinomethyl)pyridine
2,6-Bis(di-tert-butylphosphinomethyl)pyridine (CAS: 338800-13-8), with molecular formula C23H43NP2 and a molar mass of 395.54 g/mol, is a speciality phosphine ligand. It is valued for its application in homogeneous catalysis, particularly in cross-coupling reactions. Its bulky tert-butyl groups provide steric control and enhance catalyst stability, making it a key component in advanced chemical synthesis for various research and industrial applications.
- Synonyms
- C23H43NP2

Homogeneous Catalysis
This phosphine ligand serves as a crucial component in homogeneous catalysis, enabling efficient and selective chemical transformations. It is particularly effective in catalysing various cross-coupling reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds.
Organometallic Chemistry
It is employed in organometallic chemistry as a ligand to stabilise metal complexes. The steric bulk of the di-tert-butylphosphinomethyl groups influences the coordination sphere of metal centres, impacting reactivity and selectivity in catalytic cycles.
Chemical Synthesis
Used as a building block or reagent in complex organic synthesis pathways. Its unique structure contributes to controlling reaction outcomes, making it valuable for creating intricate molecular architectures in research and development settings.
| Molecular weight | 395.54 |
|---|---|
| Empirical formula | C23H43NP2 |
| Melting point | 116-119 °C |


Hazard statements
- H261In contact with water releases flammable gas
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P422
| Flash point | 67 °C / 152.6 °F |
|---|---|
| Transport (UN / ADR) | UN 2813 4.3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 14/15-36/37/38 |
| Safety statements (S) | 26-36/37/39-43 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Bis(di-tert-butylphosphinomethyl)pyridine used for?
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This compound is primarily used as a bulky phosphine ligand in homogeneous catalysis, particularly for cross-coupling reactions, and in organometallic chemistry for stabilising metal complexes in chemical synthesis.
What is the CAS number and molecular formula for 2,6-Bis(di-tert-butylphosphinomethyl)pyridine?
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The CAS number is 338800-13-8 and the molecular formula is C23H43NP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Bis(di-tert-butylphosphinomethyl)pyridine as a research chemical. We do not represent it as USP, BP, EP or any other pharmacopoeia grade.
How should 2,6-Bis(di-tert-butylphosphinomethyl)pyridine be handled and stored?
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This compound is flammable and reacts violently with water (H225, H261). It also causes skin, eye, and respiratory irritation (H315, H319, H335). Store away from water and heat, in a tightly sealed container in a cool, dry, well-ventilated area. Handle under an inert atmosphere (e.g., nitrogen or argon).
Is 2,6-Bis(di-tert-butylphosphinomethyl)pyridine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,6-Bis(di-tert-butylphosphinomethyl)pyridine, catering to customers worldwide.
How can I request a sample or quote for 2,6-Bis(di-tert-butylphosphinomethyl)pyridine?
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Please contact our sales team via the website or email to request a sample or obtain a quotation for 2,6-Bis(di-tert-butylphosphinomethyl)pyridine.
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