2-(4-Nitrophenoxy)ethanol
2-(4-Nitrophenoxy)ethanol (CAS: 16365-27-8), a chemical compound with the formula C8H9NO4 and a molecular weight of 183.16 g/mol, serves as a valuable building block in organic synthesis. This nitro-substituted aromatic alcohol is frequently employed in the chemical industry for the preparation of more complex molecules. Its specific structure allows for diverse chemical transformations, making it a useful intermediate in various research and development applications.
- IUPAC
- (4-Nitrophenyl)glycol,O-(4-Nitrophenyl)ethylene glycol
- Synonyms
- (4-Nitrophenyl)glycol,O-(4-Nitrophenyl)ethylene glycol

Organic Synthesis Intermediate
This compound acts as a key intermediate in multi-step organic syntheses. The presence of both a nitro group and a hydroxyl group allows for selective reactions, enabling the construction of diverse chemical structures for research purposes.
Building Block for Complex Molecules
As an organic building block, 2-(4-Nitrophenoxy)ethanol is utilized in the development of novel chemical entities. Its functional groups provide versatile reaction sites for chemists engaged in synthetic pathway design.
Research and Development
Primarily used in laboratory settings, this chemical supports R&D efforts in areas requiring specific aromatic and alcoholic functionalities. It is a component in exploring new materials and chemical processes.
| Molecular weight | 183.16 |
|---|---|
| Empirical formula | C8H9NO4 |
| Assay | ≥97.0% (HPLC) |
| Melting point | 82-85 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(4-Nitrophenoxy)ethanol used for?
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2-(4-Nitrophenoxy)ethanol is primarily used as an intermediate and building block in organic synthesis and in research and development laboratories for creating more complex chemical structures.
What is the CAS number and molecular formula for 2-(4-Nitrophenoxy)ethanol?
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The CAS number is 16365-27-8 and the molecular formula is C8H9NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(4-Nitrophenoxy)ethanol with a purity of ≥97.0% as determined by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling precautions for this chemical?
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This compound is a warning-level hazard, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area and avoid breathing dust.
How is 2-(4-Nitrophenoxy)ethanol packed and shipped?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all necessary regulations for safe transport. Specific packaging details are available upon request.
How can I request a sample or quote for 2-(4-Nitrophenoxy)ethanol?
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To request a sample or quote, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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