2-(4-Isothiocyanatophenoxy)ethyl tosylate
2-(4-Isothiocyanatophenoxy)ethyl tosylate (CAS: 155863-33-5), a hetero-bifunctional linker with molecular formula C16H15NO4S2, is a key synthetic building block. Its unique structure allows for the quaternisation of pyridyl-nitrogen, introducing amine or thiol reactive groups. This compound is primarily utilised in the preparation of fluorescent labels and other advanced organic synthesis applications, offering versatility for researchers and manufacturers.
- IUPAC
- 2-(4-Isothiocyanatophenoxy)ethyl p-toluenesulfonate
Preparation of Fluorescent Labels
This compound serves as a crucial building block in the synthesis of fluorescent labels. Its isothiocyanate group allows for facile conjugation to biomolecules or other substrates.
Hetero-bifunctional Linker
Utilised as a hetero-bifunctional linker, it specifically facilitates the quaternisation of pyridyl-nitrogen. This process allows for the introduction of amine or thiol reactive functionalities into target molecules.
Organic Synthesis Intermediate
As a versatile intermediate in organic synthesis, 2-(4-Isothiocyanatophenoxy)ethyl tosylate enables the construction of complex molecular architectures. Its reactive groups are valuable for various coupling and functionalisation reactions.
| Molecular weight | 349.42 |
|---|---|
| Empirical formula | C16H15NO4S2 |
| Assay | ≥98.0% (TLC) |
| Application | Hetero-bifunctional linker specially for the quaternisation of pyridyl-nitrogen in order to introduce an amine or thiol reactive group. Synthetic building block for the preparation of fluorescent labels1 |
| Melting point | 108-112 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(4-Isothiocyanatophenoxy)ethyl tosylate used for?
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2-(4-Isothiocyanatophenoxy)ethyl tosylate is used as a hetero-bifunctional linker for the quaternisation of pyridyl-nitrogen to introduce amine or thiol reactive groups, and as a synthetic building block for the preparation of fluorescent labels.
What is the CAS number and molecular formula for 2-(4-Isothiocyanatophenoxy)ethyl tosylate?
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The CAS number is 155863-33-5, and the molecular formula is C16H15NO4S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(4-Isothiocyanatophenoxy)ethyl tosylate with an assay of ≥98.0% (TLC). This product is not intended for USP, BP, EP, or any pharmacopoeial use and is supplied for research and laboratory purposes.
How should 2-(4-Isothiocyanatophenoxy)ethyl tosylate be handled safely?
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Handle with care, wearing a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust, fumes, gas, mist, vapours, and spray. Avoid contact with eyes, skin, and clothing. Ensure adequate ventilation. This compound is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. It may also cause long lasting harmful effects to aquatic life.
Is 2-(4-Isothiocyanatophenoxy)ethyl tosylate available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(4-Isothiocyanatophenoxy)ethyl tosylate.
How can I request a sample or quote for 2-(4-Isothiocyanatophenoxy)ethyl tosylate?
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Please contact our sales department via the website or telephone to request a sample or a quotation for 2-(4-Isothiocyanatophenoxy)ethyl tosylate.
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