2,4-Dimethoxypyrimidine-5-boronic acid pinacol ester
2,4-Dimethoxypyrimidine-5-boronic acid pinacol ester (CAS: 936250-17-8) is a valuable organoboron compound with a molecular weight of 266.10 g/mol. This heteroaryl boronate ester is primarily utilised in organic synthesis as a versatile building block. Its structure facilitates participation in cross-coupling reactions, making it indispensable for the construction of complex organic molecules, particularly in pharmaceutical and materials science research.
- IUPAC
- 2,6-Dimethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
- Synonyms
- C12H19BN2O42,6-Dimethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Suzuki-Miyaura Coupling Reactions
This boronic ester serves as a key coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl and vinyl halides. It is instrumental in synthesising complex biaryl and heteroaryl systems.
Pharmaceutical Intermediate Synthesis
The compound is frequently employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its pyrimidine core and boronate ester functionality allow for precise molecular elaboration.
Materials Science
It can be incorporated into the synthesis of novel organic materials, such as conjugated polymers or organic light-emitting diodes (OLEDs), where specific electronic or optical properties are desired.
Agrochemical Research
Used in the development of new agrochemicals, leveraging its structural motifs for potential herbicidal or pesticidal activity.
| Molecular weight | 266.10 |
|---|---|
| Empirical formula | C12H19BN2O4 |
| Assay | 97% |
| Melting point | 104-108 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dimethoxypyrimidine-5-boronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to create carbon-carbon bonds. It is valuable in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and molecular formula for this product?
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The CAS number is 936250-17-8 and the molecular formula is C12H19BN2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and development purposes.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance, classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with a dust mask (type N95 US), eyeshields, and gloves in a well-ventilated area. Avoid breathing dust and ensure proper P261, P305 + P351 + P338 procedures are followed.
How is 2,4-Dimethoxypyrimidine-5-boronic acid pinacol ester packed, shipped, and exported?
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This chemical is carefully packed according to international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a quote or sample?
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Please contact our sales team via the website or phone to request a quote or a sample of 2,4-Dimethoxypyrimidine-5-boronic acid pinacol ester.
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