2,4-Dimethoxybenzenesulfonyl chloride
2,4-Dimethoxybenzenesulfonyl chloride (CAS 63624-28-2) is an organic sulfur compound with the empirical formula C8H9ClO4S and a molecular weight of 236.67. This chemical is primarily utilised as a building block in organic synthesis and chemical research. Its reactivity makes it a valuable intermediate for constructing more complex molecules, particularly in the development of new pharmaceuticals and materials. It is supplied by TSS with an assay of 97%.
- Synonyms
- 2,4-Dimethoxybenzenesulfonyl chlorideBenzenesulfonyl chloride, 2,4-dimethoxy-

Organic Synthesis Intermediate
2,4-Dimethoxybenzenesulfonyl chloride serves as a versatile intermediate in various organic synthesis pathways. Its sulfonyl chloride group readily participates in reactions such as sulfonylation, enabling the introduction of the 2,4-dimethoxybenzenesulfonyl moiety into target molecules.
Pharmaceutical Research
This compound is employed in the development of novel pharmaceutical agents. It can be incorporated into the structures of potential drug candidates, contributing to their pharmacological properties and therapeutic efficacy.
Materials Science
As a building block, 2,4-Dimethoxybenzenesulfonyl chloride may find application in the synthesis of specialised polymers or functional materials. Its structure can impart specific characteristics to the final material.
| Molecular weight | 236.67 |
|---|---|
| Empirical formula | C8H9ClO4S |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 71-75 °C |


Hazard statements
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dimethoxybenzenesulfonyl chloride used for?
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2,4-Dimethoxybenzenesulfonyl chloride (CAS 63624-28-2) is primarily used as a building block in organic synthesis and chemical research, including pharmaceutical and materials science applications.
What is the CAS number and empirical formula for 2,4-Dimethoxybenzenesulfonyl chloride?
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The CAS number is 63624-28-2, and the empirical formula is C8H9ClO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Dimethoxybenzenesulfonyl chloride with an assay of 97%. This is considered a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2,4-Dimethoxybenzenesulfonyl chloride be handled safely?
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Handling requires stringent safety measures due to its corrosive nature (H314) and potential to cause skin sensitisation (H317). Use appropriate personal protective equipment including eyeshields, face shields, gloves, and respiratory protection (type N100 US/P3 EN143). Handle in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for full details.
Is 2,4-Dimethoxybenzenesulfonyl chloride a controlled substance?
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The provided data does not indicate that 2,4-Dimethoxybenzenesulfonyl chloride is a controlled substance.
How is this chemical packed and exported by TSS?
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2,4-Dimethoxybenzenesulfonyl chloride is packed according to international shipping regulations (UN 3261, Class 8, PGIII) and exported globally by TSS.
How can I request a quote or sample?
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To request a quote or sample of 2,4-Dimethoxybenzenesulfonyl chloride, please contact the TSS sales team through our website or by phone.
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