2,4-Difluoro-1,1′-biphenyl
2,4-Difluoro-1,1′-biphenyl (CAS 37847-52-2) is a difluorinated biphenyl derivative with the molecular formula C12H8F2 and a molecular weight of 190.19 g/mol. It serves as a valuable building block in organic synthesis, particularly in the development of advanced materials and pharmaceuticals. Its fluorinated nature imparts unique electronic and physical properties, making it a key intermediate for introducing difluorophenyl moieties into complex molecular structures. This compound is typically supplied at 97% purity for research and chemical synthesis applications.
- IUPAC
- 2,4-Difluorobiphenyl
- Synonyms
- 37847-52-22,4-DifluorobiphenylC12H8F2

Organic Synthesis Intermediate
Utilised as a crucial building block in multi-step organic synthesis pathways. Its structure allows for the incorporation of the 2,4-difluorophenyl group into target molecules, influencing their electronic and steric properties.
Pharmaceutical Research
Serves as an intermediate in the discovery and development of novel pharmaceutical agents. The presence of fluorine atoms can modulate drug metabolism, lipophilicity, and binding affinity.
Materials Science
Employed in the synthesis of advanced materials, potentially including liquid crystals, polymers, and organic electronic components, where fluorination can enhance stability and performance.
| Molecular weight | 190.19 |
|---|---|
| Empirical formula | C12H8F2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 61-66 °C |



Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-37/38-41-50/53 |
| Safety statements (S) | 26-39-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluoro-1,1′-biphenyl used for?
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2,4-Difluoro-1,1′-biphenyl is primarily used as a building block in organic synthesis, particularly for pharmaceutical research and the development of advanced materials. Its fluorinated structure makes it valuable for introducing specific chemical properties into target molecules.
What is the CAS number and molecular formula for 2,4-Difluoro-1,1′-biphenyl?
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The CAS number for 2,4-Difluoro-1,1′-biphenyl is 37847-52-2, and its molecular formula is C12H8F2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Difluoro-1,1′-biphenyl with an assay of 97%. This product is intended for research and chemical synthesis purposes. Tech Serve Solutions does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2,4-Difluoro-1,1′-biphenyl be handled safely?
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2,4-Difluoro-1,1′-biphenyl is classified as dangerous. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), may cause respiratory irritation (H335), and is very toxic to aquatic life (H400). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding release to the environment. Refer to the safety data sheet for comprehensive handling instructions.
How is this product packed and exported?
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This product is packed according to transport regulations, identified as UN 3077, Class 9, Packing Group III. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote?
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To request a sample or a quotation for 2,4-Difluoro-1,1′-biphenyl, please contact the Tech Serve Solutions sales team via the website or direct contact details.
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