2,3-Dimethylphenylmagnesium bromide
2,3-Dimethylphenylmagnesium bromide (CAS: 134640-85-0) is an organometallic compound with the linear formula (CH₃)₂C₆H₃MgBr and a molecular weight of 209.37 g/mol. As a Grignard reagent, it is a valuable tool in organic synthesis, primarily employed for the formation of new carbon-carbon bonds. Its reactivity makes it suitable for introducing the 2,3-dimethylphenyl group into various organic molecules, facilitating complex structure synthesis.
- Synonyms
- (CH3)2C6H3MgBr
Organic Synthesis
This Grignard reagent is extensively used in organic synthesis to introduce the 2,3-dimethylphenyl moiety into target molecules. It is particularly useful for creating carbon-carbon bonds through nucleophilic addition reactions with electrophiles such as aldehydes, ketones, and esters.
Pharmaceutical Intermediates
2,3-Dimethylphenylmagnesium bromide serves as a key building block in the synthesis of complex organic molecules, including potential pharmaceutical intermediates. Its specific structural contribution can be vital in the development of new therapeutic agents.
Material Science
The compound can be utilized in the development of novel materials. By incorporating the 2,3-dimethylphenyl group, researchers can modify the properties of polymers or other advanced materials, leading to tailored performance characteristics.
| Molecular weight | 209.37 |
|---|---|
| Linear formula | (CH3)2C6H3MgBr |
| Boiling point | 65 °C(lit.) |
| Density | 0.948 g/mL at 25 °C(lit.) |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Dimethylphenylmagnesium bromide used for?
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2,3-Dimethylphenylmagnesium bromide is primarily used in organic synthesis for the formation of carbon-carbon bonds, serving as a reagent to introduce the 2,3-dimethylphenyl group into various organic molecules. It is also employed in the synthesis of pharmaceutical intermediates and in material science applications.
What are the CAS number and formula for 2,3-Dimethylphenylmagnesium bromide?
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The CAS number for 2,3-Dimethylphenylmagnesium bromide is 134640-85-0, and its linear formula is (CH₃)₂C₆H₃MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Dimethylphenylmagnesium bromide as a 0.5 M solution in THF. We do not represent this product as USP, BP, or EP grade; it is supplied for research and development purposes. Purity information beyond the stated concentration is not available.
What are the main safety hazards associated with 2,3-Dimethylphenylmagnesium bromide?
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2,3-Dimethylphenylmagnesium bromide is a highly flammable liquid and vapour (H225). It causes serious eye irritation (H319) and may cause respiratory irritation (H335). Additionally, it is suspected of causing cancer (H351) and may form explosive peroxides. It is crucial to handle this compound with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.
How is 2,3-Dimethylphenylmagnesium bromide shipped and exported?
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2,3-Dimethylphenylmagnesium bromide is shipped and exported in compliance with stringent regulations for hazardous materials. It is classified under UN 2924, packing group II, with hazard class 8(3), indicating it is corrosive and flammable. TSS ensures all shipments adhere to international transport standards.
How can I request a sample or quote for 2,3-Dimethylphenylmagnesium bromide?
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To request a sample or a quote for 2,3-Dimethylphenylmagnesium bromide, please contact our sales department through the website or by phone. Kindly provide your specific requirements, including quantity and intended use.
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