2,3-Dimethoxybenzylamine
2,3-Dimethoxybenzylamine (CAS 4393-09-3), with the linear formula (CH3O)2C6H3CH2NH2 and a molecular weight of 167.21 g/mol, is a key organic building block. This amine compound is primarily utilised in chemical synthesis for the construction of complex molecules. Its applications include the preparation of various derivatives, such as peptide-linked dicatechols and isoindoline structures, making it valuable in research and development settings.
- Synonyms
- (CH3O)2C6H3CH2NH2

Synthesis of Peptide Derivatives
2,3-Dimethoxybenzylamine serves as a precursor in the synthesis of di-, tri-, and tetrapeptide linked dicatechol derivatives. This application is crucial for developing novel compounds with potential biological activity.
Preparation of Isoindoline Structures
The compound is employed in the synthesis of 1-aryl-2,3-dihydro-1H-isoindoles, also known as isoindolines. These heterocyclic compounds are of interest in medicinal chemistry and materials science.
Organic Building Block
As a versatile organic building block, 2,3-Dimethoxybenzylamine is used in various chemical synthesis pathways. Its reactive amine group allows for diverse functionalisation and the creation of new molecular architectures.
| Molecular weight | 167.21 |
|---|---|
| Linear formula | (CH3O)2C6H3CH2NH2 |
| Assay | 99% |
| Boiling point | 137 °C/11 mmHg(lit.) |
| Density | 1.13 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.54(lit.) |
| Application | 2,3-Dimethoxybenzylamine was used in the synthesis of di-,tri- and tetrapeptide linked dicatechol derivatives1 and 1-aryl-2,3-dihydro-1H-isoindoles (isoindolines)2. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Dimethoxybenzylamine used for?
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2,3-Dimethoxybenzylamine is used as a building block in chemical synthesis, including the preparation of di-, tri-, and tetrapeptide linked dicatechol derivatives and 1-aryl-2,3-dihydro-1H-isoindoles.
What are the CAS number and formula for 2,3-Dimethoxybenzylamine?
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The CAS number for 2,3-Dimethoxybenzylamine is 4393-09-3, and its linear formula is (CH3O)2C6H3CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Dimethoxybenzylamine with an assay of 99%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 2,3-Dimethoxybenzylamine be handled safely?
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2,3-Dimethoxybenzylamine is a Warning substance (GHS07) and is harmful if inhaled and causes skin and eye irritation (H315-H319-H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a P2 dust mask (type N95 US), ensuring adequate ventilation. Avoid breathing dust.
Is 2,3-Dimethoxybenzylamine a controlled substance?
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The provided data does not indicate that 2,3-Dimethoxybenzylamine is a controlled substance.
How is 2,3-Dimethoxybenzylamine packed and exported?
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2,3-Dimethoxybenzylamine is exported by Tech Serve Solutions in suitable packaging designed for chemical safety and stability, adhering to international shipping regulations.
How can I request a quote or sample of 2,3-Dimethoxybenzylamine?
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To request a quote or sample of 2,3-Dimethoxybenzylamine, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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