2,3-Dimercapto-1-propanol tributyrate
2,3-Dimercapto-1-propanol tributyrate (CAS 58428-97-0) is a thioester analog of triacylglycerol with a molecular weight of 334.49 g/mol. It is utilised in biochemical assays, specifically in the colorimetric analysis of lipase activity and for investigating lipase inhibition. This compound serves as a valuable reagent in enzymatic studies and organic synthesis, aiding researchers in understanding enzyme kinetics and developing new chemical entities.
- IUPAC
- BAL tributyrate
- Synonyms
- BAL tributyrate
Lipase Inhibition Assays
This compound has been employed in in vitro screening to identify medicinal plant extracts with potential antidiabetic properties by assessing their glucosidase and lipase inhibitory activities.
Lipase Activity Measurement
It is used in colorimetric microplate assays designed for the quantitative determination of lipase activity, facilitating enzyme kinetics studies.
Enzyme Specificity Analysis
Used to analyse the positional specificity of lipases, such as LipG, towards triacylglycerols employing a continuous spectrophotometric method.
| Molecular weight | 334.49 |
|---|---|
| Linear formula | CH3CH2CH2CO2CH2CH(SCOCH2CH2CH3)CH2SCOCH2CH2CH3 |
| Assay | 97% |
| Boiling point | 156-160 °C/0.15 mmHg(lit.) |
| Density | 1.083 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.495(lit.) |
| Application | 2,3-Dimercapto-1-propanol tributyrate is a thioester analog of triacylglycerol1 and has been used:• in lipase inhibition assay during in vitro screening of medicinal plants as antidiabetics with glucosidase and lipase inhibitory activities2• in colorimetric microplate assay for lipase activity3• to analyze positional specificity of LipG (lipase-encoding gene) toward triacylglycerol by a simple continuous spectrophotometric method1 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Dimercapto-1-propanol tributyrate used for?
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2,3-Dimercapto-1-propanol tributyrate is used in biochemical assays, particularly for lipase inhibition screening and the colorimetric measurement of lipase activity. It also aids in analysing the positional specificity of lipases towards triacylglycerols.
What are the CAS number and formula for 2,3-Dimercapto-1-propanol tributyrate?
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The CAS number is 58428-97-0. The linear formula is CH3CH2CH2CO2CH2CH(SCOCH2CH2CH3)CH2SCOCH2CH2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Dimercapto-1-propanol tributyrate with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2,3-Dimercapto-1-propanol tributyrate be handled safely?
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This compound is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment includes eyeshields, gloves, and a suitable respirator. Handle in a well-ventilated area.
Is 2,3-Dimercapto-1-propanol tributyrate a controlled substance?
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The provided data does not indicate that 2,3-Dimercapto-1-propanol tributyrate is a controlled substance.
How is this chemical packed, shipped, or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. For detailed information on packing, shipping, and export of 2,3-Dimercapto-1-propanol tributyrate, please contact our sales team.
How can I request a sample or quote for 2,3-Dimercapto-1-propanol tributyrate?
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To request a sample or a quotation for 2,3-Dimercapto-1-propanol tributyrate, please visit the product page on our website and use the 'Request Sample' or 'Request Quote' functionality, or contact our dedicated sales team directly.
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