2,3-Dichloropyrazine
2,3-Dichloropyrazine (CAS: 4858-85-9) is a halogenated heterocyclic compound with the molecular formula C4H2Cl2N2 and a molecular weight of 148.98 g/mol. This chemical serves as a valuable building block in organic synthesis. Its selective monosubstitution allows for efficient synthesis of various derivatives, notably alloisines, which are known potent cyclin-dependent kinase inhibitors. Available at 95% purity, it is suitable for research and development applications.
- Synonyms
- C4H2Cl2N2
Synthesis of Alloisines
Selective monosubstitution of 2,3-Dichloropyrazine enables the efficient synthesis of alloisines. These compounds are recognised as potent inhibitors of cyclin-dependent kinases, making this pyrazine derivative crucial for pharmaceutical research.
Heterocyclic Building Block
As a halogenated heterocycle, 2,3-Dichloropyrazine functions as a versatile building block. It can be incorporated into more complex molecular structures within chemical synthesis and medicinal chemistry programmes.
Research and Development
The compound is primarily used in laboratory settings for chemical synthesis and the development of novel compounds. Its specific reactivity profile makes it a useful intermediate for exploring new chemical entities.
| Molecular weight | 148.98 |
|---|---|
| Empirical formula | C4H2Cl2N2 |
| Assay | 95% |
| Density | 1.431 g/mL at 25 °C(lit.) |
| Application | Selective monosubstitution of this substrate provided an efficient synthesis of alloisines, potent cyclin-dependent kinases.1 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 102 °C / 215.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Dichloropyrazine used for?
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2,3-Dichloropyrazine is primarily used as a building block in chemical synthesis, particularly for the efficient preparation of alloisines, which are potent cyclin-dependent kinase inhibitors. It is also employed in research and development for creating novel heterocyclic compounds.
What is the CAS number and formula for 2,3-Dichloropyrazine?
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The CAS number for 2,3-Dichloropyrazine is 4858-85-9, and its empirical formula is C4H2Cl2N2.
What grade and purity does Tech Serve Solutions supply for 2,3-Dichloropyrazine?
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Tech Serve Solutions supplies 2,3-Dichloropyrazine with an assay of 95%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling 2,3-Dichloropyrazine?
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2,3-Dichloropyrazine is classified with GHS07 (Warning) and carries hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
How is 2,3-Dichloropyrazine packed, shipped, and exported?
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2,3-Dichloropyrazine is carefully packaged to ensure stability and safety during transit. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all relevant international shipping regulations.
How can I request a sample or quote for 2,3-Dichloropyrazine?
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To request a sample or a quote for 2,3-Dichloropyrazine, please contact our sales team through the website or call us directly. Please specify the quantity required for your quotation.
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