2,3′-Dibromo-4′-fluoroacetophenone
2,3′-Dibromo-4′-fluoroacetophenone (CAS 435273-49-7) is a brominated and fluorinated acetophenone derivative with the molecular formula C8H5Br2FO and a molecular weight of 295.93 g/mol. It serves as a valuable intermediate in organic synthesis, particularly within the fields of pharmaceutical research and the development of novel organic materials. Its unique structure, featuring both bromine and fluorine substituents on an acetophenone core, makes it a versatile building block for introducing specific functionalities into target molecules.
- IUPAC
- 3-Bromo-4-fluorophenacyl bromide
- Synonyms
- 3-Bromo-4-fluorophenacyl bromideC8H5Br2FO

Organic Synthesis Intermediate
This compound is widely used as a building block in the synthesis of more complex organic molecules. The presence of two bromine atoms and one fluorine atom allows for diverse synthetic transformations and the introduction of specific structural motifs.
Pharmaceutical Research
It is employed in the development of potential pharmaceutical agents, where its structure can be incorporated into drug candidates to modulate biological activity. Fluorinated and brominated aromatic compounds are common in medicinal chemistry.
Materials Science
2,3′-Dibromo-4′-fluoroacetophenone can be utilised in the creation of novel organic materials. Its reactive sites enable polymerisation or incorporation into functional materials with tailored electronic or optical properties.
| Molecular weight | 295.93 |
|---|---|
| Empirical formula | C8H5Br2FO |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 48-52 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3′-Dibromo-4′-fluoroacetophenone used for?
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2,3′-Dibromo-4′-fluoroacetophenone (CAS 435273-49-7) is primarily used as a building block in organic synthesis, particularly for pharmaceutical research and the development of new organic materials. Its specific arrangement of bromine and fluorine atoms offers unique reactivity for creating complex molecules.
What are the CAS number and formula for 2,3′-Dibromo-4′-fluoroacetophenone?
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The CAS number for 2,3′-Dibromo-4′-fluoroacetophenone is 435273-49-7, and its empirical formula is C8H5Br2FO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3′-Dibromo-4′-fluoroacetophenone with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the key safety considerations when handling this compound?
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This compound is classified with a Warning signal word, with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area and avoid breathing dust. Recommended precautionary statements include P261 (avoid breathing dust) and P305 + P351 + P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing).
How is 2,3′-Dibromo-4′-fluoroacetophenone typically shipped or exported?
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As a chemical reagent, 2,3′-Dibromo-4′-fluoroacetophenone is carefully packaged according to international shipping regulations (UN 3335 for air transport). Tech Serve Solutions is a global supplier and exporter, experienced in handling international shipments of fine chemicals.
How can I request a sample or obtain a quote for 2,3′-Dibromo-4′-fluoroacetophenone?
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To request a sample or obtain a quote for 2,3′-Dibromo-4′-fluoroacetophenone, please visit the Tech Serve Solutions website and navigate to the product page. You will find options to submit a sample request or a detailed quotation inquiry.
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