2,3,4,6-Tetrafluoroaniline
2,3,4,6-Tetrafluoroaniline (CAS: 363-73-5), with the molecular formula C6HF4NH2 and a molecular weight of 165.09 g/mol, is a fluorinated aromatic amine. This compound serves as a valuable building block and intermediate in organic synthesis, particularly in the development of novel materials and complex molecules. Its unique tetrafluoro-substituted structure offers distinct chemical properties for advanced research and development applications.
- Synonyms
- 6-Tetrafluoroaniline363-73-5HC6F4NH2

Organic Synthesis Intermediate
Serves as a key building block in the synthesis of more complex organic molecules, leveraging its fluorinated aromatic structure for specific chemical transformations. It is utilised in research and development for creating novel compounds with unique properties.
Pharmaceutical Research
Employed in the early stages of drug discovery and development as a precursor for synthesising potential pharmaceutical agents. Its fluorinated nature can impart desirable pharmacokinetic properties to candidate molecules.
Materials Science
Used in the development of advanced materials where the incorporation of fluorine atoms can modify properties such as thermal stability, chemical resistance, and electronic characteristics. This can include polymers and specialty chemicals.
| Molecular weight | 165.09 |
|---|---|
| Linear formula | HC6F4NH2 |
| Assay | 98% |
| Boiling point | 65 °C/20 mmHg(lit.) |
| Density | 1.5 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.462(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4,6-Tetrafluoroaniline used for?
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2,3,4,6-Tetrafluoroaniline is primarily used as an intermediate in organic synthesis, particularly in pharmaceutical research and materials science for the development of novel compounds.
What are the CAS number and molecular formula for 2,3,4,6-Tetrafluoroaniline?
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The CAS number for 2,3,4,6-Tetrafluoroaniline is 363-73-5, and its molecular formula is C6HF4NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,4,6-Tetrafluoroaniline with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 2,3,4,6-Tetrafluoroaniline be handled safely?
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2,3,4,6-Tetrafluoroaniline is a flammable liquid and vapour (H226) and is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields, gloves, and a full-face respirator, and ensure adequate ventilation.
How is 2,3,4,6-Tetrafluoroaniline packed and shipped?
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2,3,4,6-Tetrafluoroaniline is packed and shipped according to relevant regulations for hazardous materials, designated as UN 1993, Class 3, Packing Group III.
How can I request a quote or sample?
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To request a quote or sample of 2,3,4,6-Tetrafluoroaniline, please contact our sales department via the website or provide your details through the enquiry form.
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