2′,3′,4′,5′,6′-Pentafluoroacetophenone
2′,3′,4′,5′,6′-Pentafluoroacetophenone (CAS 652-29-9) is a fluorinated ketone with the molecular formula C6F5COCH3 and a molecular weight of 210.10. This chemical serves as a valuable building block in organic synthesis. Its primary applications lie in the asymmetric synthesis of chiral alcohols and the preparation of various fluorinated organic compounds, contributing to advancements in pharmaceutical and material science research. TSS supplies this compound with a minimum assay of 97%.
- Synonyms
- 5′,6′-PentafluoroacetophenoneC6F5COCH3
Asymmetric Synthesis of Chiral Alcohols
2′,3′,4′,5′,6′-Pentafluoroacetophenone has been utilised in the asymmetric synthesis of chiral alcohols. This process often involves the use of ketoreductases derived from microorganisms like cyanobacteria.
Synthesis of Fluorinated Organic Compounds
This compound acts as a precursor for synthesising more complex fluorinated molecules. It has been employed in the preparation of derivatives such as benzalpentafluoroacetophenone and 2,3-dihydryl-F-benzalacetophenone.
Fluorinated Building Block
As an aryl fluorinated building block, it is instrumental in introducing pentafluorophenyl groups into organic structures, facilitating the development of novel materials and pharmaceutical intermediates.
| Molecular weight | 210.10 |
|---|---|
| Linear formula | C6F5COCH3 |
| Assay | 97% |
| Boiling point | 130-131 °C(lit.) |
| Density | 1.476 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4366(lit.) |
| Application | 2′,3′,4′,5′,6′-Pentafluoroacetophenone was used in asymmetric synthesis of chiral alcohols using ketoreductase isolated from cyanobacterium Synechococcus sp. strain PCC 79421. It was also used in the synthesis of benzalpentafluoroacetophenone and 2,3-dihydryl-F-benzalacetophenone2. |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,3′,4′,5′,6′-Pentafluoroacetophenone used for?
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It is primarily used as a building block in organic synthesis, particularly for the asymmetric synthesis of chiral alcohols and in the preparation of other fluorinated organic compounds.
What is the CAS number and molecular formula?
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The CAS number is 652-29-9, and the molecular formula is C6F5COCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′,3′,4′,5′,6′-Pentafluoroacetophenone with a minimum assay of 97%. This is a research-grade chemical and not represented as USP, BP, or EP.
What are the safety and handling precautions for this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection such as a full-face respirator with an ABEK filter is recommended. It has a flash point of 66 °C (150.8 °F), indicating it is combustible.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents, including 2′,3′,4′,5′,6′-Pentafluoroacetophenone.
How can I request a sample or quote for 2′,3′,4′,5′,6′-Pentafluoroacetophenone?
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Please contact our sales team via the website or by phone to request a sample or a quotation for this product.
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