2,2-difluoro-1,3-dimethylimidazolidine
2,2-difluoro-1,3-dimethylimidazolidine (CAS 220405-40-3) is a heterocyclic organic compound with the molecular formula C5H10F2N2 and a molecular weight of 136.14 g/mol. This chemical serves as a potent nucleophilic fluorinating agent. Its unique structure and reactivity make it valuable in various synthetic chemistry applications for introducing fluorine atoms into organic molecules.
- IUPAC
- DFI
- Synonyms
- 220405-40-3C5H10F2N2

Nucleophilic Fluorination
As a primary application, 2,2-difluoro-1,3-dimethylimidazolidine acts as an effective nucleophilic fluorinating agent. It is utilised to introduce fluorine atoms into various organic substrates, which is a critical step in the synthesis of many pharmaceutical and agrochemical compounds.
Organic Synthesis Reagent
This compound is a useful building block in organic synthesis. Its difluorinated imidazolidine structure allows for specific chemical transformations, contributing to the development of novel fluorinated organic molecules with desired properties.
Heterocyclic Chemistry
Belonging to the class of Imidazolines/Imidazolidines, this chemical finds application within heterocyclic chemistry research. It can be employed in the synthesis of more complex heterocyclic systems incorporating fluorine.
| Molecular weight | 136.14 |
|---|---|
| Empirical formula | C5H10F2N2 |
| Assay | 95% |
| Density | 1.096 g/mL at 25 °C |
| Refractive index | n20/D 1.402 |
| Storage temperature | 2-8°C |
| Application | A nucleophilic fluorinating agent. |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 33 °C / 91.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2-difluoro-1,3-dimethylimidazolidine used for?
+
2,2-difluoro-1,3-dimethylimidazolidine is primarily used as a nucleophilic fluorinating agent in organic synthesis for introducing fluorine atoms into organic molecules.
What is the CAS number and molecular formula for 2,2-difluoro-1,3-dimethylimidazolidine?
+
The CAS number is 220405-40-3, and the molecular formula is C5H10F2N2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,2-difluoro-1,3-dimethylimidazolidine with an assay of 95%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
What are the key safety hazards associated with this chemical?
+
This chemical is classified as flammable (H226) and causes severe skin burns and eye damage (H314). It requires careful handling with appropriate personal protective equipment, and storage should be at 2-8°C.
How is this product packed and shipped?
+
The product is shipped under UN 2920, Hazard Class 3(8), Packing Group II, indicating it is a corrosive liquid, flammable, n.o.s. Please contact us for specific packing and export details.
How can I request a sample or quote?
+
To request a sample or a quote for 2,2-difluoro-1,3-dimethylimidazolidine, please use the contact form on our website or call our sales team directly.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis