(1S,2S)-(+)-Norpseudoephedrine
(1S,2S)-(+)-Norpseudoephedrine (CAS: 492-39-7) is a chiral amino alcohol derived from pseudoephedrine. As a stereospecific compound, it serves as a valuable building block in asymmetric synthesis and chiral chemistry. It is utilised in the synthesis of complex organic molecules where precise stereochemical control is paramount. Tech Serve Solutions offers this compound for research and development purposes.
- IUPAC
- (+)-Cathine,(+)-Pseudonorephedrine,(1S,2S)-2-Amino-1-phenyl-1-propanol,D-(+)-Norpseudoephedrine
- Synonyms
- (+)-Cathine(+)-Pseudonorephedrine(1S,2S)-2-Amino-1-phenyl-1-propanolD-(+)-Norpseudoephedrine

Chiral Auxiliary in Asymmetric Synthesis
The stereocentres present in (1S,2S)-(+)-Norpseudoephedrine make it a useful chiral auxiliary. It can be temporarily incorporated into a molecule to direct the stereochemical outcome of subsequent reactions.
Building Block for Chiral Molecules
This compound acts as a fundamental chiral building block for the synthesis of more complex stereochemically pure organic compounds, including pharmaceutical intermediates.
Research and Development
Utilised in academic and industrial laboratories for exploring new synthetic methodologies and developing novel chiral compounds.
| Assay | ≥98.0% (NT) |
|---|---|
| Optical activity | [α]/D +34.0±2.0°, c = 3.5 in ethanol |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule IV; regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-(+)-Norpseudoephedrine used for?
+
(1S,2S)-(+)-Norpseudoephedrine is primarily used as a chiral auxiliary and a building block in asymmetric synthesis and the development of complex organic molecules.
What is the CAS number and chemical formula for (1S,2S)-(+)-Norpseudoephedrine?
+
The CAS number is 492-39-7. The chemical formula is not provided in the data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1S,2S)-(+)-Norpseudoephedrine with a purity of ≥98.0% (NT). This is a research grade; we do not represent it as USP, BP, or EP grade.
How should (1S,2S)-(+)-Norpseudoephedrine be handled safely?
+
This compound is acutely toxic if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with a dust mask (N95), eyeshields, face shield, and gloves in a well-ventilated area.
Is (1S,2S)-(+)-Norpseudoephedrine a controlled substance?
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Yes, (1S,2S)-(+)-Norpseudoephedrine is regulated under US DEA Schedule IV and CDSA. It is not available from Canada.
How is (1S,2S)-(+)-Norpseudoephedrine packed and shipped?
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(1S,2S)-(+)-Norpseudoephedrine is shipped as UN 2811, Class 6.1, Packing Group III. It should be stored at 2-8°C.
How can I request a quote or sample?
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Please contact the Tech Serve Solutions sales team directly through our website or by phone to request a quote or a sample.
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