(1S, 2S)-1,2-Bis(4-fluorophenyl)ethylenediamine dihydrochloride
(1S, 2S)-1,2-Bis(4-fluorophenyl)ethylenediamine dihydrochloride (CAS: 1052707-11-5) is a chiral diamine salt with the molecular formula C14H14F2N2 · 2HCl and a molecular weight of 321.19 g/mol. This compound serves as a valuable building block and ligand in asymmetric synthesis and chemical research. Its specific stereochemistry makes it useful for developing chiral catalysts and facilitating stereoselective reactions in organic chemistry.
- IUPAC
- (1S, 2S)-1,2-Bis(4-fluorophenyl)-1,2-ethanediamine dihydrochloride
- Synonyms
- 1052707-11-5C14H14F2N2 · 2HCl(1S, 2S)-1,2-Bis(4-fluorophenyl)-1,2-ethanediamine dihydrochloride

Chiral Ligand in Asymmetric Catalysis
This diamine salt can function as a chiral ligand in transition metal-catalyzed asymmetric reactions, enabling the synthesis of enantiomerically enriched products.
Chiral Building Block
It serves as a key chiral synthon for the construction of more complex chiral molecules, including pharmaceuticals and advanced materials.
Reagent in Stereoselective Synthesis
The defined stereochemistry of this compound makes it a useful reagent for controlling stereochemical outcomes in various organic transformations.
| Molecular weight | 321.19 |
|---|---|
| Empirical formula | C14H14F2N2 · 2HCl |
| Assay | 97% |
| Optical activity | [α]22/D -25.0°, c = 1 in H2O |
| Melting point | 247-251 °C |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S, 2S)-1,2-Bis(4-fluorophenyl)ethylenediamine dihydrochloride primarily used for?
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It is primarily used as a chiral building block and ligand in asymmetric synthesis and stereoselective reactions.
What is the CAS number and molecular formula for this compound?
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The CAS number is 1052707-11-5, and the molecular formula is C14H14F2N2 · 2HCl.
What grade and purity does Tech Serve Solutions supply for (1S, 2S)-1,2-Bis(4-fluorophenyl)ethylenediamine dihydrochloride?
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Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent it as USP, BP, EP, or pharmacopoeia grade.
How should (1S, 2S)-1,2-Bis(4-fluorophenyl)ethylenediamine dihydrochloride be handled safely?
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This compound is classified as harmful if swallowed (H302) and requires handling with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Avoid ingestion and dust inhalation.
Is this compound suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (1S, 2S)-1,2-Bis(4-fluorophenyl)ethylenediamine dihydrochloride.
How can I request a quote or sample?
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Please contact our sales team via our website or direct inquiry channels to request a quote or sample for (1S, 2S)-1,2-Bis(4-fluorophenyl)ethylenediamine dihydrochloride.
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