(1R,2R)-trans-N-Boc-1,2-cyclohexanediamine
(1R,2R)-trans-N-Boc-1,2-cyclohexanediamine (CAS 146504-07-6) is a chiral building block with a molecular weight of 214.30 g/mol. This protected diamine is a valuable intermediate in asymmetric synthesis, facilitating the creation of enantiomerically pure compounds. Its specific stereochemistry and protected amine functionality make it crucial for constructing complex molecules in pharmaceutical research and fine chemical synthesis.
- IUPAC
- (1R)-trans-N-Boc-1,2-diaminocyclohexane
- Synonyms
- 146504-07-6C11H22N2O2(1R)-trans-N-Boc-1,2-diaminocyclohexane
Asymmetric Synthesis
Utilised as a chiral ligand or auxiliary in asymmetric catalysis to induce stereoselectivity in chemical reactions. It is instrumental in the preparation of enantiomerically enriched target molecules.
Pharmaceutical Intermediates
Serves as a key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its defined stereochemistry is critical for the biological activity of the final drug product.
Organic Synthesis
A versatile reagent for introducing chiral diamine functionalities into organic molecules. The Boc protecting group allows for selective deprotection and further functionalisation.
Chiral Ligand Development
Can be modified to create novel chiral ligands for various metal-catalysed transformations, enhancing enantioselectivity and reaction efficiency.
| Molecular weight | 214.30 |
|---|---|
| Empirical formula | C11H22N2O2 |
| Assay | ≥96.5%97% |
| Optical activity | [α]/D -26±2°, c = 1 in chloroform |
| Optical purity | ee: ≥99.0% |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and other complex organic molecules.
What is the CAS number and formula for (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine?
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The CAS number is 146504-07-6 and the empirical formula is C11H22N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine with an assay of ≥96.5% or 97%, and an optical purity (ee) of ≥99.0%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
What are the safety considerations when handling this chemical?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (type N100 or P3 filters), must be used. Handle in a well-ventilated area.
How is this chemical packed and shipped?
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Tech Serve Solutions ensures appropriate packaging for safe transport according to UN 3259, Class 8, Packing Group III regulations, and handles global export.
How can I request a sample or quote?
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To request a sample or quote for (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine, please contact our sales department through the website or by phone.
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