1H-Benzotriazol-1-ylmethyl isocyanide
1H-Benzotriazol-1-ylmethyl isocyanide (CAS 87022-42-2, C8H6N4) is a specialised organic compound with a molecular weight of 158.16 g/mol. Supplied by Tech Serve Solutions, this reagent is primarily utilised in organic synthesis for C-C bond formation. Its applications include participation in Passerini and Ugi-type reactions, as well as heterocyclisation with imines. It is also a precursor for preparing specific silver polymeric complexes.
- IUPAC
- 1-(Isocyanomethyl)-1H-benzotriazole
Passerini Condensation
This compound serves as a key reactant in the Passerini condensation reaction, a multi-component reaction used to synthesise alpha-acyloxy carboxamides.
Ugi Type Reactions
It participates in Ugi-type reactions, which are powerful tools for the construction of complex molecular scaffolds through the assembly of multiple simple components.
Heterocyclisation
1H-Benzotriazol-1-ylmethyl isocyanide is employed in heterocyclisation reactions with imines, facilitating the synthesis of various nitrogen-containing heterocyclic compounds.
Polymeric Complex Preparation
This isocyanide can be used in the preparation of silver (isocyanomethyl)benzotriazole polymeric complexes, finding potential applications in coordination chemistry.
| Molecular weight | 158.16 |
|---|---|
| Empirical formula | C8H6N4 |
| Assay | 94% |
| Application | Reactant for:• Passerini condensation1• Ugi type reactions2• Heterocyclization with imines3• Preparation of silver (isocyanomethyl)benzotriazole polymeric complex4 |
| Melting point | 80-84 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1H-Benzotriazol-1-ylmethyl isocyanide used for?
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1H-Benzotriazol-1-ylmethyl isocyanide is used as a reactant in organic synthesis, particularly for C-C bond formation, Passerini condensation, Ugi type reactions, and heterocyclisation with imines.
What are the CAS number and chemical formula for 1H-Benzotriazol-1-ylmethyl isocyanide?
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The CAS number is 87022-42-2 and the empirical formula is C8H6N4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1H-Benzotriazol-1-ylmethyl isocyanide with a minimum assay of 94%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main hazards associated with 1H-Benzotriazol-1-ylmethyl isocyanide?
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1H-Benzotriazol-1-ylmethyl isocyanide is classified with the GHS07 symbol and a Warning signal word. It carries hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used.
How is 1H-Benzotriazol-1-ylmethyl isocyanide packed, shipped, and exported?
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1H-Benzotriazol-1-ylmethyl isocyanide is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations. Specific packaging details are available upon request.
How can I request a sample or quote for 1H-Benzotriazol-1-ylmethyl isocyanide?
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To request a sample or a quote for 1H-Benzotriazol-1-ylmethyl isocyanide, please contact our sales department through the website or by phone.
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