(−)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid

CAS 73891-15-3C16H24O14Chemical Synthesis

(−)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid (CAS: 73891-15-3) is a C16H24O14 compound with a molecular weight of 440.35. As a crown ether derivative, it is utilised in chemical synthesis and complexation reactions. It serves as a chiral NMR solvating agent for determining enantiomeric purity and configuration, and as a reactant in the preparation of potential antitumor agents.

Synonyms: 12-tetracarboxylic acid73891-15-3C16H24O14

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(−)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid (C16H24O14) — chemical structure, CAS 73891-15-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisCrown EthersSynthetic Reagents

01 /Applications

Chiral NMR Solvating Agent

Used to determine the enantiomeric purity and absolute configuration of β-amino acids through chiral NMR spectroscopy.

Reactant in Pharmaceutical Synthesis

Employed as a reactant in the synthesis of NCL-1, a potential antitumor agent, specifically a lysine-specific demethylase 1 inhibitor.

Crown Ether Applications

As a functionalised crown ether, it is applicable in complexation chemistry and as a synthetic reagent in organic synthesis.

02 /Properties

Molecular weight	440.35
Empirical formula	C16H24O14
Optical activity	[α]20/D −65 in 1% methanol
Application	Reactant for:Preparation of optically active lysine-specific demethylase 1 inhibitor NCL-1 as a potential antitumor agent1Used as:Chiral NMR solvating agent for determining the enantiomeric purity and absolute configuration of β-amino acids2
Melting point	208-210 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

73891-15-3

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (–)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid used for?

(–)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid is used as a chiral NMR solvating agent for determining enantiomeric purity and as a reactant in the synthesis of potential antitumor agents.

What are the CAS number and formula for this compound?

The CAS number is 73891-15-3 and the molecular formula is C16H24O14.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. The specific assay and grade are available upon request, and it is not represented as USP, BP, or EP grade.

How should (–)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid be handled?

This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.