10-Deacetylbaccatin III from Taxus baccata
10-Deacetylbaccatin III (CAS: 32981-86-5, C29H36O10) is a crucial taxane diterpenoid isolated from *Taxus baccata*. This compound serves as a key intermediate in the semi-synthesis of the potent anti-cancer drug paclitaxel (Taxol). It is also instrumental in scientific research for elucidating the complex biosynthetic pathways of taxanes. TSS offers this high-purity chemical for advanced research and pharmaceutical intermediate applications.
Paclitaxel Synthesis
10-Deacetylbaccatin III is a vital precursor for the semi-synthesis of paclitaxel, a widely used chemotherapeutic agent. Its structure provides the core taxane skeleton required for the final drug molecule.
Taxane Biosynthesis Research
This compound is employed in biochemical studies to investigate and understand the intricate metabolic pathways responsible for taxane production in yew trees.
Chemical Intermediate
Utilised as a starting material or intermediate in the synthesis of other complex natural products and drug analogues within pharmaceutical research and development.
| Molecular weight | 544.59 |
|---|---|
| Empirical formula | C29H36O10 |
| Assay | ≥95% (HPLC) |
| Storage temperature | 2-8°C |
| Application | 10-Deacetylbaccatin III is used as a chemical intermediate in the preparation of the anti-cancer drug paclitaxel (Taxol). It is used to study the taxol biosynthetic pathway1,2,3. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 10-Deacetylbaccatin III used for?
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10-Deacetylbaccatin III (CAS: 32981-86-5) is primarily used as a chemical intermediate in the synthesis of the anti-cancer drug paclitaxel. It is also used in research to study the taxol biosynthetic pathway.
What are the CAS number and formula for 10-Deacetylbaccatin III?
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The CAS number for 10-Deacetylbaccatin III is 32981-86-5, and its molecular formula is C29H36O10.
What grade and purity does Tech Serve Solutions supply for 10-Deacetylbaccatin III?
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Tech Serve Solutions supplies 10-Deacetylbaccatin III with a minimum purity of ≥95% (HPLC). This product is intended for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety precautions when handling 10-Deacetylbaccatin III?
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When handling 10-Deacetylbaccatin III, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Consult the Safety Data Sheet for comprehensive handling information.
How is 10-Deacetylbaccatin III stored and shipped?
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10-Deacetylbaccatin III requires storage at 2-8°C. TSS ensures secure packaging and appropriate handling for global export, adhering to all relevant shipping regulations for fine chemicals.
How can I request a sample or quote for 10-Deacetylbaccatin III?
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To request a sample or a quotation for 10-Deacetylbaccatin III, please contact our sales department through the website or by direct inquiry, providing your contact details and the quantity required.
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