1-(Trimethylsiloxy)cyclohexene
1-(Trimethylsiloxy)cyclohexene (CAS: 6651-36-1), with the molecular formula C6H9OSi(CH3)3 and a molar mass of 170.32 g/mol, is a versatile organic building block. It functions as an enol ether, enabling its use as a key intermediate in the synthesis of complex organic molecules and natural products. This compound is valuable in chemical synthesis, particularly for creating diverse molecular structures.
- IUPAC
- 1-Cyclohexenyloxytrimethylsilane,Cyclohexanone enol trimethylsilyl ether
- Synonyms
- 1-CyclohexenyloxytrimethylsilaneCyclohexanone enol trimethylsilyl ether

Synthesis of Complex Organic Molecules
1-(Trimethylsiloxy)cyclohexene serves as a crucial intermediate in the construction of intricate organic compounds. Its enol ether functionality allows for strategic incorporation into synthetic pathways leading to natural products and other valuable molecules.
Precursor for Octalone Derivatives
This compound has been employed in the one-pot synthesis of Δ1,9-octalone. This specific application highlights its utility in forming fused ring systems essential in various areas of organic chemistry.
Building Block in Organic Synthesis
As an organic building block and an enol ether, 1-(Trimethylsiloxy)cyclohexene offers synthetic chemists a reactive handle for carbon-carbon bond formation and functional group transformations.
| Molecular weight | 170.32 |
|---|---|
| Linear formula | C6H9OSi(CH3)3 |
| Assay | 99% |
| Boiling point | 64-65 °C/15 mmHg(lit.) |
| Density | 0.875 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.447(lit.) |
| Application | 1-(Trimethylsiloxy)cyclohexene was used in one-pot synthesis of Δ1,9- octalone1. It is intermediate to many complex compounds including natural products. |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 41 °C / 105.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Trimethylsiloxy)cyclohexene used for?
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1-(Trimethylsiloxy)cyclohexene is used as a building block in chemical synthesis, particularly as an intermediate for complex compounds and in the preparation of Δ1,9-octalone.
What is the CAS number and molecular formula for 1-(Trimethylsiloxy)cyclohexene?
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The CAS number is 6651-36-1 and the molecular formula is C6H9OSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Trimethylsiloxy)cyclohexene with an assay of 99%. This is a technical/research grade material and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 1-(Trimethylsiloxy)cyclohexene be handled safely?
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1-(Trimethylsiloxy)cyclohexene is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Ensure sources of ignition are avoided.
Is 1-(Trimethylsiloxy)cyclohexene shipped internationally?
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Yes, Tech Serve Solutions, as a global supplier and exporter since 1998, ships 1-(Trimethylsiloxy)cyclohexene worldwide.
How can I request a sample or quote for 1-(Trimethylsiloxy)cyclohexene?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 1-(Trimethylsiloxy)cyclohexene.
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