1-Phenylsemicarbazide
1-Phenylsemicarbazide (CAS: 103-03-7) is an organic compound with the linear formula C6H5NHNHCONH2 and a molecular weight of 151.17 g/mol. This white to off-white solid serves as a key building block in organic synthesis, particularly for creating heterocyclic compounds. It is frequently employed in the development of novel pyrazole derivatives and related structures with potential applications in various chemical research fields.

Synthesis of Pyrazole Derivatives
1-Phenylsemicarbazide is utilised in cyclocondensation reactions with specific trihaloalkenones to synthesise substituted 1H-1-phenylpyrazoles. This application is crucial for researchers exploring new heterocyclic scaffolds.
Preparation of Organic Building Blocks
As an organic building block, it facilitates the construction of more complex molecules. Its structure allows for derivatisation and incorporation into diverse chemical syntheses.
Reagent in Chemical Synthesis
This compound functions as a valuable reagent in organic synthesis, enabling the creation of various substituted urea and pyrazole structures. It is used in academic and industrial research laboratories.
| Molecular weight | 151.17 |
|---|---|
| Linear formula | C6H5NHNHCONH2 |
| Assay | 99% |
| Solubility | acetone: very soluble(lit.)alcohol: very soluble(lit.)benzene: slightly soluble(lit.)cold water: slightly soluble(lit.)diethyl ether: slightly soluble(lit.)hot water: very soluble(lit.)methanol: very soluble(lit.) |
| Application | 1-Phenylsemicarbazide was used in the synthesis of a series of alkyl(aryl/heteroaryl) substituted 3-trifluoromethyl-1H-1-phenylpyrazoles and alkyl 3-carboxylate analogs by the cyclocondensation reactions with 4-alkoxy-1,1,1-trihaloalk-3-en-2-ones1. |
| Melting point | 171-174 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Phenylsemicarbazide (CAS 103-03-7) used for?
+
1-Phenylsemicarbazide is primarily used as a building block in organic synthesis, notably for the preparation of pyrazole derivatives and other heterocyclic compounds. It also serves as a reagent in various chemical synthesis pathways.
What is the CAS number and chemical formula for 1-Phenylsemicarbazide?
+
The CAS number for 1-Phenylsemicarbazide is 103-03-7, and its linear chemical formula is C6H5NHNHCONH2.
What grade and purity does Tech Serve Solutions supply for 1-Phenylsemicarbazide?
+
Tech Serve Solutions supplies 1-Phenylsemicarbazide with an assay of 99%. This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Phenylsemicarbazide be handled safely?
+
1-Phenylsemicarbazide is classified under GHS07 with the signal word 'Warning' due to H302 (Harmful if swallowed). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
Is 1-Phenylsemicarbazide available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-Phenylsemicarbazide, and can facilitate export orders worldwide.
How can I request a sample or quote for 1-Phenylsemicarbazide?
+
To request a sample or obtain a quote for 1-Phenylsemicarbazide, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis