1-Phenylpiperazine
1-Phenylpiperazine (CAS 92-54-6, C10H14N2) is a heterocyclic organic compound with a molecular weight of 162.23 g/mol. It is widely recognised as a valuable building block in organic synthesis and a key intermediate in the development of various biologically active molecules. Its utility spans research in cell biology and the chemical synthesis of complex pharmaceutical agents and other fine chemicals, making it an essential reagent in advanced chemical research and development.
- IUPAC
- N-Phenyldiethylenediamine

Pharmaceutical Intermediate
1-Phenylpiperazine serves as a crucial intermediate in the synthesis of numerous pharmaceutical compounds. Its structural motif is found in several classes of drugs, including antipsychotics and antidepressants, highlighting its significance in medicinal chemistry.
Research Chemical
This compound is extensively used in academic and industrial research laboratories as a building block for novel molecular architectures. It aids in exploring new chemical reactions and developing new compounds with potential biological activity.
Reagent in Organic Synthesis
As a versatile reagent, 1-Phenylpiperazine participates in various organic transformations. Its reactivity allows for the introduction of the phenylpiperazine moiety into larger, more complex molecules.
Chemical Biology Studies
Used in studies focusing on cellular mechanisms and receptor interactions, 1-Phenylpiperazine contributes to understanding biological pathways and drug target engagement.
| Molecular weight | 162.23 |
|---|---|
| Empirical formula | C10H14N2 |
| Assay | 99% |
| Boiling point | 286 °C(lit.) |
| Density | 1.062 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.588(lit.) |


Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 140 °C / 284 °F |
| Transport (UN / ADR) | UN 2922 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-24-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Htr3a(15561)rat ... Drd2(24318), Htr1a(24473) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Phenylpiperazine used for?
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1-Phenylpiperazine is primarily used as a building block in organic synthesis, a key intermediate in the development of pharmaceuticals, and a reagent in chemical biology research.
What are the CAS number and chemical formula for 1-Phenylpiperazine?
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The CAS number for 1-Phenylpiperazine is 92-54-6, and its chemical formula is C10H14N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Phenylpiperazine with an assay of 99%. This product is intended for research and technical use and is not represented as USP, BP, or EP grade.
How should 1-Phenylpiperazine be handled safely?
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1-Phenylpiperazine is classified as Dangerous Goods. It is corrosive and toxic if swallowed, in contact with skin, or if inhaled. Always handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is 1-Phenylpiperazine a controlled substance?
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While 1-Phenylpiperazine is a precursor for certain controlled substances, it is not typically listed as a controlled substance itself in most jurisdictions. Please check your local regulations.
How is 1-Phenylpiperazine packed and exported?
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1-Phenylpiperazine is packed in compliance with international dangerous goods regulations for safe transport. TSS exports this chemical globally, adhering to all relevant shipping and customs requirements.
How can I request a quote or sample for 1-Phenylpiperazine?
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To request a quote or sample of 1-Phenylpiperazine, please use the contact form on our website or email our sales department directly with your requirements.
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