1-Phenyl-3-(trimethylsilyl)-2-propyn-1-ol
1-Phenyl-3-(trimethylsilyl)-2-propyn-1-ol (CAS: 89530-34-7) is an organic building block with the molecular formula C12H16OSi and a molecular weight of 204.34 g/mol. This compound is characterised by its alkyne and silyl functionalities, making it valuable in organic synthesis. It is primarily utilised as a key intermediate and a versatile building block in the creation of more complex molecules within chemical research and development.
- IUPAC
- α-[(Trimethylsilyl)ethynyl]benzenemethanol

Organic Synthesis Intermediate
Serves as a crucial intermediate in the synthesis of complex organic molecules. Its unique structure, featuring a phenyl group, a hydroxyl group, and a trimethylsilyl-protected alkyne, allows for selective chemical transformations.
Building Block for Novel Compounds
Functions as a versatile building block in the construction of new chemical entities. The trimethylsilyl group can be selectively removed, revealing a terminal alkyne for further reactions like click chemistry or Sonogashira coupling.
Research and Development
Employed in academic and industrial research laboratories for exploring new synthetic pathways and developing novel materials or pharmaceutical candidates. Its reactivity profile makes it an interesting substrate for various chemical studies.
| Molecular weight | 204.34 |
|---|---|
| Empirical formula | C12H16OSi |
| Assay | 97% |
| Density | 0.9610 g/mL at 25 °C |
| Refractive index | n20/D 1.5193 |
| Storage temperature | 2-8°C |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Phenyl-3-(trimethylsilyl)-2-propyn-1-ol used for?
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1-Phenyl-3-(trimethylsilyl)-2-propyn-1-ol is used as an intermediate and building block in organic synthesis for creating complex molecules and exploring new chemical research.
What is the CAS number and formula for 1-Phenyl-3-(trimethylsilyl)-2-propyn-1-ol?
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The CAS number is 89530-34-7 and the empirical formula is C12H16OSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent it as USP, BP, or EP grade. For specific batch analysis, please consult the Certificate of Analysis.
How should 1-Phenyl-3-(trimethylsilyl)-2-propyn-1-ol be handled safely?
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This compound is classified as an irritant (H319). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure good ventilation. Avoid contact with eyes and skin. Store at 2-8°C.
How is 1-Phenyl-3-(trimethylsilyl)-2-propyn-1-ol packed, shipped, and exported?
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Products are carefully packed in accordance with international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team via the website or by phone. Specify the product name and CAS number (89530-34-7) in your inquiry.
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