1-Pentyne
1-Pentyne (CAS: 627-19-0; Formula: CH3CH2CH2C≡CH; MW: 68.12) is a terminal alkyne supplied by Tech Serve Solutions. This colourless liquid serves as a versatile building block in organic synthesis. Its primary applications include the preparation of lithium acetylides for asymmetric synthesis and the creation of complex heterocyclic compounds such as naphthopyran derivatives. With a purity of 99%, 1-Pentyne is suitable for various research and development needs.
Preparation of Lithium Acetylides
1-Pentyne is utilised in the synthesis of lithium acetylides. These intermediates are crucial for asymmetric synthesis, particularly in the creation of α,α-dibranched propargyl sulfinamides.
Synthesis of Naphthopyran Derivatives
This terminal alkyne serves as a precursor in the synthesis of specific organic compounds, including 7-hydroxy-10-methoxy-3H-naphtho[2.1-b]pyrans.
Organic Synthesis Building Block
As a functionalised alkyne, 1-Pentyne acts as a fundamental building block in diverse organic synthesis pathways, enabling the construction of more complex molecular architectures.
| Molecular weight | 68.12 |
|---|---|
| Linear formula | CH3CH2CH2C≡CH |
| Assay | 99% |
| Boiling point | 40 °C(lit.) |
| Density | 0.691 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.385(lit.) |
| Vapour pressure | 6.8 psi (20 °C) |
| Melting point | −106-−105 °C(lit.) |
| Application | 1-Pentyne has been used in preparation of:• lithium acetylides, required for asymmetric synthesis of α,α-dibranched propargyl sulfinamides1• 7-hydroxy-10-methoxy-3H-naphtho[2.1-b]pyrans2 |
Hazard statements
- H225Highly flammable liquid and vapour
- H304May be fatal if swallowed and enters airways
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
- P331Do NOT induce vomiting
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -20 °C / -4 °F |
| Transport (UN / ADR) | UN 3295BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-36/37/38-65 |
| Safety statements (S) | 16-26-36-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Pentyne used for?
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1-Pentyne is used as a building block in organic synthesis, notably for preparing lithium acetylides used in asymmetric synthesis and for creating compounds like 7-hydroxy-10-methoxy-3H-naphtho[2.1-b]pyrans.
What is the CAS number and formula for 1-Pentyne?
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The CAS number for 1-Pentyne is 627-19-0, and its linear formula is CH3CH2CH2C≡CH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Pentyne with an assay of 99%. TSS does not represent this product as USP, BP, or EP grade.
How should 1-Pentyne be handled safely?
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1-Pentyne is highly flammable (Flash Point -20 °C) and may cause skin irritation, serious eye irritation, and respiratory irritation. It is also an aspiration hazard. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a respirator, in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet for detailed handling instructions.
How is 1-Pentyne packed and shipped?
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1-Pentyne is shipped under UN 3295, Packaging Group II, reflecting its hazardous nature. Specific packaging details are available upon request.
How can I request a quote or sample for 1-Pentyne?
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Please contact our sales team via the website or phone to request a quotation or a sample of 1-Pentyne.
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