1-Octyne
1-Octyne (CAS: 629-05-0), a terminal alkyne with the molecular formula C8H14 and a molecular weight of 110.20 g/mol, is a versatile organic building block. Characterised by its C≡CH functional group, it serves as a key intermediate in various chemical syntheses. Its properties make it useful in research settings, including as a mechanism-based inhibitor in biochemical studies.
Chemical Synthesis
1-Octyne is a valuable terminal alkyne utilised as a foundational building block in organic synthesis. Its triple bond readily participates in a variety of addition and coupling reactions, enabling the construction of more complex molecular architectures.
Biochemical Research
This compound has been employed as a mechanism-based inhibitor in studies involving enzymes such as AlkB, a nonheme di-iron alkane monooxygenase. This application highlights its utility in probing enzymatic mechanisms.
Organic Building Block
As a linear C8 alkyne, 1-Octyne functions as a fundamental organic building block for introducing an eight-carbon chain with terminal unsaturation into target molecules.
| Molecular weight | 110.20 |
|---|---|
| Linear formula | CH3(CH2)5C≡CH |
| Assay | 97% |
| Boiling point | 127-128 °C(lit.) |
| Density | 0.747 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.416(lit.) |
| Vapour pressure | 37.7 mmHg (37.7 °C) |
| Melting point | −80 °C(lit.) |
| Impurities tested | ≤3% 1-bromohexane |
| Application | 1-Octyne was used as a mechanism-based inhibitor of AlkB (nonheme di-iron alkane monooxygenase)1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H304May be fatal if swallowed and enters airways
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P301IF SWALLOWED
- P331Do NOT induce vomiting
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 16 °C / 60.8 °F |
| Transport (UN / ADR) | UN 3295BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-65 |
| Safety statements (S) | 16-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Octyne used for?
+
1-Octyne is primarily used as an organic building block in chemical synthesis and for biochemical research, including as a mechanism-based inhibitor of enzymes like AlkB.
What is the CAS number and formula for 1-Octyne?
+
The CAS number for 1-Octyne is 629-05-0, and its linear formula is CH3(CH2)5C≡CH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-Octyne with a minimum assay of 97%. This product is intended for research and technical applications; TSS does not represent it as USP, BP, or EP grade.
How should 1-Octyne be handled safely?
+
1-Octyne is a highly flammable liquid and vapour (Flash Point: 16 °C) and may be fatal if swallowed and enters airways (H225, H304). Handling requires appropriate personal protective equipment including eyeshields, gloves, and suitable respiratory protection. Store away from ignition sources in a well-ventilated area (P210).
How is 1-Octyne packed, shipped, and exported?
+
1-Octyne is shipped internationally by TSS according to stringent regulations for hazardous materials, including UN 3295 classification. Packaging is designed to ensure product integrity and safety during transit.
How can I request a sample or quote for 1-Octyne?
+
To request a sample or a quotation for 1-Octyne, please contact our sales team via the website or by telephone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis