1-Dodecanoyl-sn-glycero-3-phosphocholine
1-Dodecanoyl-sn-glycero-3-phosphocholine (CAS: 20559-18-6) is a zwitterionic glycerophospholipid with the molecular formula C20H42NO7P and a molecular weight of 439.52 g/mol. It is a valuable biochemical reagent widely utilised in cell biology research. Its amphipathic nature makes it effective in biological membrane studies and as a detergent in protein solubilisation and purification, particularly for membrane proteins.
- IUPAC
- L-α-Lysophosphatidylcholine, lauroyl,Lysolecithin, lauroyl

Detergent for Membrane Protein Studies
This compound functions as a zwitterionic detergent, facilitating the solubilisation and purification of integral membrane proteins. Its amphipathic properties help maintain protein structure and function in detergent micelles.
Nanodisc Preparations
It is employed in the preparation of nanodiscs, which are important tools for studying membrane proteins in a near-native environment. This aids in structural and functional characterisation of complex membrane protein systems.
Lipid Research and Membrane Biophysics
As a glycerophospholipid, it is used in studies of lipid metabolism, membrane biophysics, and the formation of liposomes and other lipid-based structures for drug delivery or research applications.
| Molecular weight | 439.52 |
|---|---|
| Empirical formula | C20H42NO7P |
| Assay | ~99% |
| Storage temperature | −20°C |
| Description | zwitterionic |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Dodecanoyl-sn-glycero-3-phosphocholine used for?
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1-Dodecanoyl-sn-glycero-3-phosphocholine is primarily used as a zwitterionic detergent in biochemical research, particularly for membrane protein solubilisation, purification, and in the preparation of nanodiscs for membrane protein studies. It also finds applications in lipid research and membrane biophysics.
What are the CAS number and formula for 1-Dodecanoyl-sn-glycero-3-phosphocholine?
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The CAS number for 1-Dodecanoyl-sn-glycero-3-phosphocholine is 20559-18-6, and its empirical formula is C20H42NO7P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Dodecanoyl-sn-glycero-3-phosphocholine with an assay of approximately 99%. This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 1-Dodecanoyl-sn-glycero-3-phosphocholine be handled?
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1-Dodecanoyl-sn-glycero-3-phosphocholine is classified under WGK Germany 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area to avoid exposure. Consult the Safety Data Sheet (SDS) for detailed hazard information and handling precautions.
How is 1-Dodecanoyl-sn-glycero-3-phosphocholine packed and shipped?
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This product is typically stored at -20°C. It is carefully packed and exported by Tech Serve Solutions in compliance with all relevant shipping regulations for chemical reagents.
How can I request a sample or quote for 1-Dodecanoyl-sn-glycero-3-phosphocholine?
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To request a sample or a quote for 1-Dodecanoyl-sn-glycero-3-phosphocholine, please contact our sales department through the TSS website or by telephone. Our team will be pleased to assist you with your inquiry.
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